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Table 3 Risk factors for cancer

From: Association between drug intake and incidence of malignancies in patients with Juvenile Idiopathic Arthritis: a nested case–control study

 

n missing

Case

n (%)

Control

n (%)

OR (95 %-CI)a

Total

 

37 (22.8)

125 (77.2)

 

Parental cancer history

    

 No

3

18 (51.4)

78 (62.9)

1.00 (Ref.)

 Yes

 

17 (48.6)

46 (37.1)

1.94 (0.92;4.13)

Ever Smoked

    

 No

1

16 (44.4)

66 (52.8)

1.00 (Ref.)

 Yes

 

20 (55.6)

59 (47.2)

1.49 (0.66;3.41)

Currently smoking

    

 No

0

29 (78.4)

94 (75.2)

1.00 (Ref.)

 Yes

 

8 (21.6)

31 (24.8)

0.84 (0.32;2.15)

CT

    

 No

0

9 (24.3)

60 (48.0)

1.00 (Ref.)

 Yes

 

28 (75.7)

65 (52.0)

0.95 (0.51;1.76)

Scintigraphy

    

 No

0

17 (45.9)

91 (72.8)

1.00 (Ref.)

 Yes

 

20 (54.1)

34 (27.2)

2.01 (1.15;3.50)

X-ray (dentist)

    

 0–5

20

16 (47.1)

46 (42.6)

1.0 (Ref.)

 6–10

 

10 (29.4)

29 (26.9)

0.96 (0.37;2.48)

 11–20

 

5 (14.7)

19 (17.6)

0.81 (0.25;2.69)

 >20

 

3 (8.8)

14 (13.0)

0.65 (0.16;2.71)

X-ray

    

 0–5

15

1 (2.8)

11 (9.9)

1.00 (Ref.)

 6–10

 

2 (5.6)

14 (12.6)

1.85 (0.15;22.58)

 11–20

 

10 (27.8)

29 (26.1)

4.27 (0.46;39.39)

 >20

 

23 (63.9)

57 (51.4)

4.34 (0.52;36.01)

Nuclear radiation therapy

    

 No

1

26 (70.3)

114 (91.9)

1.00 (Ref.)

 Yes

 

11 (29.7)

10 (8.1)

3.04 (1.25;7.36)

  1. OR odds ratio, CI confidence interval, aOR of conditional (fixed-effects) logistic regression analysis with cancer (yes/no) as outcome