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Table 2 Mean levels of the urinary miRNA’s in the supernatant and pellet in different groups at visit 1

From: Relationship of cell-free urine MicroRNA with lupus nephritis in children

 

Mean ± SEa

P valueb

Controlsc (n = 10)

SLE Group (n = 10)

LN Group (n = 14)

 

Urine Supernatant

    

miR125a

5.83 ± 0.59

5.67 ± 0.53

6.66 ± 0.48

NS

miR127

6.65 ± 0.60

5.24 ± 0.54

5.26 ± 0.51

NS

miR146a

7.98 ± 0.93

7.61 ± 0.84

7.15 ± 0.76

NS

miR150

4.08 ± 0.73

4.08 ± 0.65

4.88 ± 0.62

NS

miR155

4.72 ± 0.64

4.03 ± 0.58

5.23 ± 0.53

NS

Urine Pellet

    

miR125a

9.45 ± 0.67

9.89 ± 0.60

10.21 ± 0.55

NS

miR127

8.87 ± 0.69

9.10 ± 0.62

8.59 ± 0.56

NS

miR146a

11.02 ± 0.52

10.74 ± 0.44

10.77 ± 0.40

NS

miR150

9.14 ± 0.62

9.34 ± 0.55

9.89 ± 0.53

NS

miR155

9.20 ± 0.62

9.10 ± 0.56

10.01 ± 0.51

NS

  1. Values of miRNA’s are relative expression normalized to RNU48
  2. miR micro RNA, JIA Juvenile Idiopathic Arthritis, LN Lupus Nephritis
  3. aSE, standard Error
  4. b P-values based on a t- test comparing means of all different groups , NS, not significant with p-value >0.05
  5. cControls include fibromyalgia and the Juvenile idiopathic arthritis patients together and their values were almost identical
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Pediatric Rheumatology

ISSN: 1546-0096