Table 4 Variability between verses among pediatric rheumatologists and pediatric nephrologists in decision to perform repeat biopsy
Pediatric Rheumatologists | Pediatric Nephrologists | |
|---|---|---|
Respondents* | 109 | 68 |
“When do you repeat a kidney biopsy in a patient with proliferative SLE nephritis? | ||
“After the initial induction period, regardless of response to treatment” | 7 (6 %) | 11 (16 %) |
“After the initial induction period, only if there is no response to treatment” | 44 (40 %) | 31 (46 %) |
“After the initial induction period, if there is only partial response to treatment” | 26 (24 %) | 19 (28 %) |
“After remission and before withdrawal of all immunosuppression” | 6 (6 %) | 3 (4 %) |
“After lupus flare with worsening in urine sediment, proteinuria, or kidney function” | 75 (69 %) | 47 (69 %) |
“I do not routinely perform a repeat biopsy in lupus nephritis patients” | 35 (32 %) | 17 (25 %) |
“When do you repeat a kidney biopsy in a patient with membranous SLE nephritis? | ||
“After the initial induction period, regardless of response to treatment” | 4 (4 %) | 2 (3 %) |
“After the initial induction period, only if there is no response to treatment” | 33 (31 %) | 24 (36 %) |
“After the initial induction period, if there is only partial response to treatment” | 14 (13 %) | 12 (18 %) |
“After remission and before withdrawal of all immunosuppression” | 6 (6 %) | 2 (3 %) |
“After lupus flare with worsening in urine sediment, proteinuria, or kidney function” | 71 (66 %) | 48 (72 %) |
“I do not routinely perform a repeat biopsy in lupus nephritis patients” | 37 (35 %) | 17 (25 %) |