Table 1 Main clinical features in patients with uncertain genetic results
From: Genetic profiling of autoinflammatory disorders in patients with periodic fever: a prospective study
Symptoms | Uncertain genetic results (n = 24) | Univariate OR (95% CI) | p value |
|---|---|---|---|
Response to corticosteroids, n (%) # | Â | Â | Â |
Yes | 7/19 (36.8) | 0.2 (0.04-0.9) | 0.03 |
No | 10/13 (76.9) | ||
Myalgia, n (%) | Â | Â | Â |
Yes | 9/21 (42.9) | 0.3 (0.1-1.1) | 0.06 |
No | 15/21 (71.4) | Â | |
Abdominal pain and/or diarrhea, n (%) | Â | Â | Â |
Yes | 19/29 (65.5) | 3.0 (0.8-11.8) | 0.1 |
No | 5/13 (38.5) | Â | |
Arthralgia, n (%) | Â | Â | Â |
Yes | 11/22 (50.0) | 0.5 (0.2-1.9) | 0.3 |
No | 13/20 (65.0) | Â | |
Tonsillitis, n (%) | Â | Â | Â |
Yes | 14/22 (63.6) | 1.8 (0.5-6.0) | 0.4 |
No | 10/20 (50.0) | Â | |
Toracic pain, n (%) | Â | Â | Â |
Yes | 2/6 (33.3) | 0.3 (0.1-2.0) | 0.4f |
No | 22/36 (61.1) | Â | |
Rash, n (%) | Â | Â | Â |
Yes | 7/14 (50.0) | 0.6 (0.2-2.4) | 0.5 |
No | 17/28 (60.7) | Â | |
Cold-induced crisis, n (%) | Â | Â | Â |
Yes | 3/4 (75.0) | 2.4 (0.2-25.5) | 0.6f |
No | 21/38 (55.3) | Â | |
Response to colchicine, n (%)* | Â | Â | Â |
Yes | 3/5 (60.0) | 1.1 (0.1-11.6) | 1.0f |
No | 4/7 (57.1) | Â | |
Splenomegaly, n (%) | Â | Â | Â |
Yes | 3/6 (50.0) | 0.7 (0.1-4.0) | 1.0f |
No | 21/36 (58.3) | Â |