From: Clinical presentations and outcomes of Filipino juvenile systemic lupus erythematosus
Category | At the time of diagnosis | during the disease course | ||
---|---|---|---|---|
No. | % | No. | % | |
Mucocutaneous
Manifestations | 71 | 91.0 | 72 | 92.3 |
Malar rash | 51 | 65.3 | 60 | 76.9 |
Discoid rash | 25 | 32.0 | 28 | 35.8 |
Photosensitivity | 43 | 55.1 | 57 | 73.0 |
Oral ulcers | 42 | 53.8 | 53 | 67.9 |
Alopecia | 31 | 39.7 | 41 | 52.5 |
Musculoskeletal
Involvement | 32 | 41.0 | 42 | 53.8 |
Arthritis | 17 | 21.7 | 31 | 39.7 |
Arthralgia | 24 | 30.7 | 40 | 51.2 |
Pulmonary Involvement | 11 | 14.1 | 17 | 21.7 |
Pleuritis/Pleural effusion | 11 | 14.1 | 16 | 20.5 |
Cardiac Involvement | 13 | 16.6 | 17 | 21.7 |
Pericarditis/Pericardial Effusion | 12 | 15.3 | 14 | 20.5 |
Valvular anomaly on Echocardiography | 8 | 10.2 | 8 | 10.2 |
Ventricular/atrial Hypertrophy | 4 | 5.1 | 5 | 6.4 |
Renal involvement | 49 | 62.8 | 56 | 71.7 |
Hematuria | 19 | 24.3 | 26 | 33.3 |
Proteinuria | 32 | 41.0 | 20 | 25.6 |
CNS involvement | 24 | 30.7 | 25 | 32.0 |
Seizure | 12 | 15.3 | 15 | 19.2 |
Behavioral changes | 9 | 11.5 | 10 | 12.8 |
Hematologic
Involvement | 37 | 47.4 | 54 | 69.2 |
Laboratory | ||||
Cellular casts | 11 | 14.1 | 22 | 28.2 |
Increased creatinine | 6 | 7.6 | 11 | 14.1 |
Hemolytic anemia | 7 | 8.9 | 8 | 10.2 |
Leukocytopenia | 12 | 15.3 | 25 | 32.0 |
Lymphocytopenia | 17 | 21.7 | 32 | 41.0 |
Thrombocytopenia | 11 | 14.1 | 20 | 25.6 |
Low C3 | 7 | 8.9 | 7 | 8.9 |