Table 1 Clinical and laboratorial manifestations and treatment of refractory thrombocytopenia
From: Splenectomy for refractory thrombocytopenia in juvenile systemic lupus erythematosus
Patient | SSR | ACS | MJS |
|---|---|---|---|
Age (years) | 16 | 12 | 12 |
Months between JSLE/splenectomy | 1 | 38 | 10 |
Previous treatment | Pd, MP, CYC | Pd, MP, HCQ, IVG, AZA, C, RTX | Pd, MP, HCQ, IVG, AZA, C, MMF, RTX |
Platelet count | 3,000/mL | 7,000/mL | 10,000/mL |
Splenectomy | Held | Held | Indicated (cancelled due to bone marrow hypoplasia-toxicity?) |
Platelet count (time after surgery) | 107,000/mL (2 w) 469,000/mL (2 m) | 140,000/mL (1 d) 396,000/mL (3 d) | - |
Recurrences | none | 1 month after | - |