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Table 2 Serum cytokine levels in healthy pediatric controls and in patients with JIA.

From: Elevated serum levels of soluble CD154 in children with juvenile idiopathic arthritis

 

Controls

N = 81

Cases

N = 77

P value

Cytokine

Mean

Median

IQR

Mean

Median

IQR

 

IL1β

6.8

0.6

0–3.5

120.9

11

3.4–73

<0.0001

IL2

1.3

0

0–0

12.9

0

0–0

0.31

IL4

0.6

0

0–0.2

5

0

0–0.9

0.07

IL5

0.2

0

0–0

7.7

0.4

0–1.6

<0.0001

IL6

1.7

0.6

0–1.8

196.7

14.2

4.8–114

<0.0001

IL8

2.3

2

0–4.2

149.5

19.3

0.6–91.3

<0.0001

IL10

3.3

2.0

1.6–3.2

8.2

2.9

1.3–8.4

0.07

IL12

5.4

0

0–3.2

3.9

0

0–1.4

0.44

IL13

0.8

0

0–0.4

178.7

19

0–181.1

< 0.0001

sCD154

58.2

19

4.2–73.2

336.1

211.4

148.7–363.9

< 0.0001

IFNγ

0.3

0

0–0

4

0

0–0

0.001

sIL2R

796.8

785.1

611.8–962.9

1125

967.3

553.7–1436.9

0.026

TNFα

2.9

0

0–0

88.5

15

0–70.7

<0.0001

  1. IQR, Interquartile range; IL, Interleukin; sCD154, soluble CD154; IFNγ, interferon-γ; sIL2R, soluble IL2 receptor; TNFα, tumor necrosis factor-α; All values median (range) are expressed in pg/ml.
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Pediatric Rheumatology

ISSN: 1546-0096