Popliteal venous thrombosis in juvenile arthritis with Baker cysts: report of 3 cases

Table 1 Thrombophilia risk factors present (+) or absent (-) in our patients. Only those risk factors present in at least one of our patients are shown.

	Patient 1	Patient 2	Patient 3
Prothrombin G20210A mutation	-	+	-
Factor V A4070G mutation*	-	+	-
Lipoprotein (a) increase	+	+	-
Methylenetetrahydrofolatereductase (MTHFR) mutation**	+	+	+
PAI-1 4G/4G mutation	+	-	+
β fibrinogen G455A mutation	+	+	+
Lupus antibody²	+	-	-
Factor VIII increase³	-	+	+

All mutations were heterozygous except for the homozygous MTHFR mutation A1298C in patient 1.
*This is not the factor V Leiden mutation.
**MTHFR mutations were homozygous A1298C in patient 1, heterozygous A1298C in patient 2 and C677T in patient 3.
PAI = Plasminogen Activator Inhibitor.
²Lupus antibody was an IgM against beta-2-glycoprotein.
³Factor VIII increases were around 200% of the expected and present at the time of thrombosis, but may also be explained as acute phase reaction.

ISSN: 1546-0096