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Proximal (to MCP/MTP joints) skin sclerosis/induration of the skin
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Minor criteria (At least two required)
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Cutaneous
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Sclerodactyly
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Peripheral vascular
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Raynaud's phenomenon
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Nailfold capillary abnormalities
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Digital tip ulcers
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Gastrointestinal
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Dysphagia
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| |
Gastro-esophageal reflux
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Cardiac
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Arrhythmias
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Heart failure
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Renal
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Renal crisis
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New onset arterial hypertension
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Respiratory
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Pulmonary fibrosis (HRCT/radiograph)
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Decreased DLCO
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Pulmonary arterial hypertension
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Neurologic
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Neuropathy
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| |
Carpal tunnel syndrome
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Musculoskeletal
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Tendon friction rubs
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| |
Arthritis
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Myositis
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Serologic
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Antinuclear antibodies
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| |
SSc selective autoantibodies
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| |
(anticentromere, anti-topoisomerase I (Scl 70), anti-fibrillarin, anti-PM-Scl, anti-fibrillin or anti-RNA polymerase I or III)
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