TGFβ1 levels disease activity. TGFβ1 serum concentrations (pg/ml) and disease activity. In the box and whisker plots, the horizontal line in the middle of the box represents the median, the bottom and top of the box represent one standard deviation from the mean, and the lines (whiskers) represent 2 standard deviations. Individual outlyers are represented by the filled squares above 2 SDs. Patient numbers: Active – 21 patients, Non active-23, Indeterminate-11.