Skip to main content

Developing of a new scale for assessing the adherence to colchicine treatment in pediatric patients with FMF

Introduction

Familial Mediterranean Fever (FMF) is a disease characterized by attacks and colchicine is the medication considered most effective in reducing the intensity and frequency of attacks. Adherence to the medication regiment is important not only to manage FMF symptoms, but also to prevent amyloidosis.

Objective

In this study, it is aimed to develop and assess the validity and reliability of the adherence scale for colchicine treatment in pediatric FMF patients.

Methods

This study was planned as a methodological study to development of scale for assessment of adherence to treatment of pediatric patients with FMF using colchicine treatment. Pediatric patients (2-18 ages) with FMF using colchicine at least 6 months and accepted to participate in the study constitute the sample of the study. “Data collection forms about the sociodemographic and medical information (demographic, clinical and laboratory findings) of patients”, “adherence scale for colchicine in pediatric FMF patients” and “Morisky Medication Adherence Scale” were used as data collection instruments. If the patient was under 7 years old, his parents filled the forms.

Results

There were 150 patients with FMF enrolled for the validation of the study. The median age of the patients was 11.11±4.02 (min.2.74-max.17.99) and 48.7% of them were male. The median of the attack frequency was 11,00±10,74(min. 0-max 52) and 60.7% of the participants had irregular attacks.

For internal consistency, Cronbach's alpha was 0,728 for “adherence scale for colchicine in pediatric FMF patients”. Also, there was a positive and significant correlation (r: 0.843, p

Conclusion

Based on these results, using this scale for the purpose of the assessment and follow up of adherence to treatment of pediatric patients with FMF who use colchicine is recommended.

Author information

Affiliations

Authors

Corresponding author

Correspondence to C Acikel.

Rights and permissions

Open Access  This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/.

The Creative Commons Public Domain Dedication waiver (https://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Yesilkaya, S., Acikel, C., Fidanci, B. et al. Developing of a new scale for assessing the adherence to colchicine treatment in pediatric patients with FMF. Pediatr Rheumatol 13, P109 (2015). https://doi.org/10.1186/1546-0096-13-S1-P109

Download citation

Keywords

  • Internal Consistency
  • Pediatric Patient
  • Colchicine
  • Amyloidosis
  • Medication Adherence