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Forever interesting disease: Kawasaki vasculitis – case series


Kawasaki disease (KD) typically presents in children younger then 5y as a febrile illness with mucocutaneous changes. If untreated, KD can result in coronary aneurisms in 25% patients.


Analysis of 6 patients diagnosed as KD, at Children's Hospital Sarajevo from 2008 to 2014.


Retrospective analysis of clinical features, coronary artery abnormalities and treatment outcome.


Youngest patient was 3 months, oldest 13 years, far more boys 83% (5/6). Seasonal peak was during winter (Jan-Feb) in 50%. Clinicall presentation (figure 2) was consistent with literature. All patient had high inflammatory markers, anemia (patients 1, 2, 5), thrombocitosis. Patient 1. had incomplete KD, with coronary artery aneurisms seen before therapy. Completely responded well to one dose of IVIG. Patient 2.was diagnosed od day 7 of fever; received IVIG, but had unusually prolonged systemic inflammation requesting second IVIG dose and pulses of IVMP plus MTX. Patient 3. is a child with suspected primary immunodeficiency (neutrophil dysfunction in observation). Patient 5. presented with pleuropneumonia requesting active pleural dreinage and had prolonged inflammation. Responded well to second IVIG + IVMP. Patient 6.had splinter haemorragies on his nails.


KD is diagnosed on clinical basis with supportive laboratory evidence and imaging. Once identified, timely initiation of treatment is imperative in order to quell the inflammatory response and decrease the incidence of long-term sequellae, specifically coronary artery aneurisms. Longitudinall follow-up should be implemented based on risk stratification and individualised to each patient.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Selmanovic, V., Omercahic-Dizdarevic, A., Mesihovic-Dinarevic, S. et al. Forever interesting disease: Kawasaki vasculitis – case series. Pediatr Rheumatol 12 (Suppl 1), P367 (2014).

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