Genetic association with articular damage in patients with juvenile idiopathic arthritis (JIA)

Table 1

	JADI				MRI
	Gene	P	OR	n	Gene	P	OR	n
Baseline (associated with damage)	upstream RANKL	0.0004	1.98	n=110 vs n=119	upstream DKK1	0.0022	NA	n=109 vs n=24
	RANKL promoter	0.0009	1.91		upstream DKK1	0.0037	NA
	upstream RANKL	0.0036	0.57
	OPG intronic	0.0094	1.68
Followup (associated with improvement)	IL1R2 intronic	0.0024	0.48	n= 55 vs n=118	IL6 promoter	0.0047	5.19	n=32 vs n=53
	IL1R2 promoter	0.0043	2.05		IL19 intron	0.0065	3.52
	upstream IL1R2	0.0050	0.50		between IL1R2 and IL1R1	0.0076	0.38
	RANK intronic	0.0090	9.21	n= 55 vs n=17
Followup (associated with no change)	downstream OPG	0.0081	3.16	n=101 vs n=17	IL20 promoter	0.0084	3.38	n=23 vs n=29

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