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  • Invited speaker presentation
  • Open Access

Auto-inflammatory diseases

  • 1
Pediatric Rheumatology201412 (Suppl 1) :I24

https://doi.org/10.1186/1546-0096-12-S1-I24

  • Published:

Keywords

  • Public Health
  • Chronic Inflammation
  • Great Efficacy
  • Recent Recommendation
  • Important Progress

Auto-inflammatory diseases are a rapidly moving field, where the description of new entities, the understanding of the pathogenesis and the treatment has shown important progress in the past years. This group of conditions include monogenic auto-inflammatory diseases, like FMF, CAPS, TRAPS and MKD, and non-monogenic auto-inflammatory diseases, like PFAPA, SoJIA, CRMO, and Behçet. The most common clinical feature is recurrent fever and a pro-inflammatory cytokine, IL-1, is a key molecule involved in the pathogenesis of these diseases. The treatment aims to control chronic inflammation and blocking agents of IL-1 have shown a great efficacy in most of these diseases.

The aim of the presentation is to make an update on the diagnosis and the treatment and review the recent recommendations elaborated by experts’ consensus through the SHARE project.

Disclosure of interest

None declared.

Authors’ Affiliations

(1)
Pediatric Rheumatology Romande, CHUV, University of Lausanne, Lausanne, Switzerland

Copyright

© Hofer; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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