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Figure 4 | Pediatric Rheumatology

Figure 4

From: The presence of high mobility group box-1 and soluble receptor for advanced glycation end-products in juvenile idiopathic arthritis and juvenile systemic lupus erythematosus

Figure 4

Receiveroperatingcharacteristiccurveof HMGB1 and C-reactive protein (CRP) serum levels insystemiconset JIA. Among the participants with systemic onset JIA, levels of HMGB1 and CRP were significantly higher in patients with hepatosplenomegaly and serositis compared to those without these clinical characteristics. HMGB1 was more sensitive than CRP in detecting hepatosplenomegaly and serositis in these patients, as shown by receiver operating characteristics (ROC) curve. The area under the curve for HMGB1 was 0.9412, the mean ± 95% confidence, using a cut off value of 19595 pg/ml for HMGB1 and136 mg/l for CRP.

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Pediatric Rheumatology

ISSN: 1546-0096