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Table 2 Patterns of autoantibodies collected in 17 of 192 patients from the Nordic juvenile idiopathic arthritis database

From: Anti-type II collagen antibodies, anti-CCP, IgA RF and IgM RF are associated with joint damage, assessed eight years after onset of juvenile idiopathic arthritis (JIA)

Patient No Age at time of onset IgM RF Cut-off IgA RF Cut-off IgG Anti-CCP Cut-off IgG Anti-Collagen II Cut-off Articular damage¤ JIA category# Cumulative number of joints affected during the first eight years of disease
Years > 5 U/ml > 9 U/ml > 7 U/ml > 29 U/ml
1 4.4 5.7 - - - Missing Systemic 4
2 12.8 6.0 - - - - Oligoarticular persistent 2
3 13.5 23.0 - - - - Undifferentiated* 1
4 9.4 5.5 - - - - Oligoarticular persistent 2
5 9.3 - 13.0 - - - Enthesitis-related arthritis 4
6 1.5 - 14.0 - - 1 Oligoarticular extended 18
7 13.2 64.0 17.0 - - 1 Polyarticular RF-positive 13
8 13.3 132.0 67.0 ≥ 340 - 1 Undifferentiated** 18
9 10.9 17.0 - ≥ 340 - 1 Oligoarticular extended 24
10 1.1 - - 9.8 - - Systemic 6
11 11.8 - 23.0 15.0 - - Enthesitis-related arthritis 2
12 11.0 - 11.0 12.0 94.3 1 Polyarticular RF-negative 19
13 11.7 - - - 35.9 1 Polyarticular RF-negative 34
14 4.0 - - - 46.6 - Enthesitis-related arthritis 13
15 4.8 - - - 30.4 - Oligoarticular extended 9
16 4.3 - - - 72.9 - Undifferentiated*** 2
17 8.1 - - - 230.8 Missing Oligoarticular persistent 1
  1. ¤Articular damage at eight-year follow-up according to JADI-A (score 0–72) [19].
  2. #ILAR Edmonton criteria after eight years of disease [2].
  3. *Oligoarticular persistent joint pattern and presence of IgM rheumatoid factor on two occasions more than three months apart.
  4. **Polyarticular pattern from onset and psoriasis in first degree relative.
  5. ***Oligoarticular persistent joint pattern and psoriasis in first degree relative.