Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis

Sztajnbok, Flavio; Boechat, Neio L F; Ribeiro, Samantha B; Oliveira, Sheila K F; Sztajnbok, Denise C N; Sant’Anna, Clemax C

doi:10.1186/1546-0096-12-17

Pediatric Rheumatology

Table 2 Epidemiological and clinical data besides TST and T. SPOT.TB/ELISPOT results from the 24 cases

From: Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis

Case/gender	JIA	Age at diagnosis (months)	Time Dx-T0 (months)	Age T0 (months)	T0	T3	T12	Follow up (months)	LTBI
1	P	72	16	88	TST 0	TST0	TST 0	57
M	P	72	16	88	Elispot -	Elispot -	Elispot -	57
2*	O	20	90	110	TST 0	TST 4	TST 10	58	yes
F	O	20	90	110	Elispot -	Elispot -	Elispot -	58	yes
3	P	152	2	154	TST 7	TST 0	TST 0	59	yes
F	P	152	2	154	Elispot -	Elispot -	Elispot -	59	yes
4	O	192	24	216	TST 0	TST 0	TST 0	59
F	O	192	24	216	Elispot -	Elispot -	Elispot -	59
5*	P	130	6	136	TST 5	TST 19	TST 12	55	yes
F	P	130	6	136	Elispot -	Elispot -	Elispot -	55	yes
6*	O	88	1	89	TST 0	TST 0	TST 0	56
M	O	88	1	89	Elispot -	Elispot -	Elispot -	56
7*	S	102	2	104	TST 0	TST 10	TST 10	56	Yes
F	S	102	2	104	Elispot -	Elispot -	Elispot -	56	Yes
8	O	84	106	190	TST 14	TST 10	TST 15	56	Yes
F	O	84	106	190	Elispot -	Elispot -	Elispot -	56	Yes
9	O	108	99	207	TST 13	TST 15	TST 13	56	Yes
M	O	108	99	207	Elispot -	Elispot -	Elispot -	56	Yes
10	O	86	30	116	TST 0	TST 0	TST 0	55
F	O	86	30	116	Elispot -	Elispot -	Elispot -	55
11	S	113	1	114	TST 0	TST 0	TST 0	53
F	S	113	1	114	Elispot -	Elispot -	Elispot -	53
12	S	24	46	70	TST 0	TST 0	TST 0	37
F	S	24	46	70	Elispot -	Elispot +	Elispot -	37
13	P	139	4	143	TST 0	TST 0	TST 10	52	Yes
M	P	139	4	143	Elispot -	Elispot +	Elispot +	52	Yes
14*	P	111	12	123	TST 3	TST 3	TST 0	51
M	P	111	12	123	Elispot -	Elispot -	Elispot -	51
15*	O	85	108	193	TST 0	TST 0	TST 0	50
F	O	85	108	193	Elispot -	Elispot -	Elispot -	50
16	S	54	48	102	TST 1	TST 0	TST 0	29
F	S	54	48	102	Elispot -	Elispot -	Elispot -	29
17	O	60	90	150	TST 0	TST 0	TST 0	29
F	O	60	90	150	Elispot -	Elispot -	Elispot -	29
18	S	66	1	67	TST 0	TST 0	TST 0	28
F	S	66	1	67	Elispot -	Elispot -	Elispot -	28
19*	P	156	32	188	TST 0	TST 0	TST 23	25	Yes
M	P	156	32	188	Elispot -	Elispot -	Elispot -	25	Yes
20	P	160	1	161	TST 0	TST 0	TST 0	19
F	P	160	1	161	Elispot -	Elispot -	Elispot -	19
21	P	61	1	62	TST 0	TST 0	TST 0	18
F	P	61	1	62	Elispot -	Elispot -	Elispot -	18
22	O	35	1	36	TST 0	TST 10	TST 10	60	Yes
F	O	35	1	36	Elispot -	Elispot -	Elispot -	60	Yes
23	P	96	2	98	TST 0	TST 0	TST 0	57
F	P	96	2	98	Elispot -	Elispot -	Elispot -	57
24*	P	216	1	217	TST 5	TST 4	TST 2	57	Yes
M	P	216	1	217	Elispot -	Elispot -	Elispot -	57	Yes

Legend:
• JIA = JIA subtypes: O = oligoarticular JIA; P= polyarticular JIA; S= systemic JIA.
• (*) = epidemiological hystory positive for TB.
• TST: in millimeters.
• T.SPOT.TB/ELISPOT : (-) = negative; (+) = positive.
• T0: study onset; T3: 3rd month; T12: 12th month.

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ISSN: 1546-0096

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