Volume 11 Supplement 2

Proceedings of 20th Pediatric Rheumatology European Society (PReS) Congress

Open Access

PReS-FINAL-2017: Systemic onset juvenile idiopathic arthritis (SOJIA)-a 5-year survey in a pediatric rheumatology department

  • A Čengić1,
  • A Omerčahić Dizdarević1,
  • V Selmanović1 and
  • S Mesihović Dinarević2
Pediatric Rheumatology201311(Suppl 2):P30

https://doi.org/10.1186/1546-0096-11-S2-P30

Published: 5 December 2013

Introduction

Systemic onset Juvenile Idiopathic Arthritis (SoJIA) is rare pediatric disease, it accounts for 10% of children with Juvenile Idiopathic Arthritis. The onset of disese can be vary nonspecific and may suggest bacterial or viral infection, malignancy or other rheumatic disease. It is highly characterised by its extra-articular systemic illness features and, in some ways, it resembles a fever of unknown origin. Diagnosis is mostly clinical by using ILAR criteria (International League of Associations for Rheumatology).

Objectives

To assess the frequency of presenting symptoms and laboratory findings in SoJIA patients over 5 years period.

Methods

This is retrospective study on all SoJIA patients diagnosed in department of pediatric rheumatology from January 2008 until January 2013 using ILAR criteria. The medical records were reviewed. In each case age, gender, presenting symptoms and laboratory data were reviewed.

Results

During the study period 12 patients were diagnosed, mean age at diagnosis was 8.9 years (14 month to 15 years). There were an equal distribution of genders. Mean duration of fever at the time of diagnosis was 22.4 days. At the presentation all 12 children had fever longer than 2 weeks (100%), 8 children had salmon rash (66%), 9 had arthritis (75%, 100% developed arthritis in the first year of disease), 8 had splenomegaly (66%), only 2 hepatomegaly (16%), 10 children had generalised lymphadenopathy (83%), 5 had serositis (40%). Mild anaemia was present in 75% of patients, leucocytosis in 92%, thrombocytosis in 58%. Elevated sedimentation rate and C reactive protein (CRP) were found in 100% patient. Antinuclear antibody (ANA) was positive in 4 patients (30%).

Conclusion

Data from our study were consistent with clinical and laboratory findings from other studies and related literature. ANA was positive in 4 children (30%), which is probably false positive result.

Disclosure of interest

None declared.

Authors’ Affiliations

(1)
Pediatric Alergoimmunorheumatology, Clinical Centre University of Sarajevo
(2)
Pediatric Cardiology, Pediatric Clinic, Clinical Centre University of Sarajevo

Copyright

© Čengić et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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