Volume 11 Supplement 2

Proceedings of 20th Pediatric Rheumatology European Society (PReS) Congress

Open Access

PReS-FINAL-2123: Feto-maternal outcome in patients with systemic sclerosis

  • SE Maher1 and
  • FM Ismail2
Pediatric Rheumatology201311(Suppl 2):P135

https://doi.org/10.1186/1546-0096-11-S2-P135

Published: 5 December 2013

Introduction

Progressive systemic sclerosis is a life threating disease typically involve the heart, lungs, and other organs. pregnancy is a stressful condition that can affect the course of the disease.

Objectives

To study the maternal and fetal outcomes in pregnant women with Systemic Sclerosis (ssc) and to analyze the possible associated risk factors.

Methods

Twenty pregnant women with ssc and twenty age-matched low risk pregnant women were recruited in this study. Patients were evaluated clinically and laboratory at the entry of the study and at monthly intervals. Different pregnancy outcome measures were studied. Impacts of pregnancy on scleroderma patients were determined during and after pregnancy. The possible associated risk factors were analyzed.

Results

Twenty ssc pregnant women were recruited in this study with a mean age 29.6 ± 3. Eight (40%) of them had limited ssc, and twelve (60%) had diffuse type. Pregnancies were complicated by maternal flare of underlying disease in six (30%) pregnant patients. Six patients (30%) had preterm labor. Four patients (20%) had small for gestational age (SGA) infants, two of them (10%) had intra uterine growth retardation (IUGR). Two patients (10%), with diffuse type, fulfilled criteria of antiphospholipid syndrome (APS) but unfortunately the pregnancy ended in miscarriage. Eight (40%) full-term infants were born two of them were SGA, 2 cases with miscarriage due to renal crisis and pulmonary hypertension and another two cases with intra uterine fetal death (IUFD). The live birth rate was 14/20 (70%) in ssc group.

Conclusion

Women with ssc can safely have healthy pregnancies if pregnancy is planned when the disease is stable and managed by a multidisciplinary team during pregnancy.

Disclosure of interest

None declared.

Authors’ Affiliations

(1)
Pediatric, El Minia University
(2)
Rheumatology, El Minia University

Copyright

© Maher and Ismail; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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