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Table 4 Stepwise multiple regression analysis of variables related to health-related quality of life

From: Mothers’ reports of the difficulties that their children experience in taking methotrexate for Juvenile Idiopathic Arthritis and how these impact on quality of life

Model   B S.E. β P R 2
Physical summary score
1 age -.583 .284 -.168 .042 .028
2 age -.463 .268 -.134 .086 .150
Number of limited joints -1.340 .296 -.350 .000  
3 age -.475 .265 -.137 .075 .176
Number of limited joints -1.145 .306 -.299 .000  
Number of active joints -1.094 .510 -.170 .034  
4 age -.586 .263 -.169 .027 .214
Number of limited joints -1.058 .302 -.276 .001  
Number of active joints -1.064 .500 -.166 .035  
MTX administration route -5.691 2.181 -.198 .010  
5 age -.200 .325 -.058 .539 .235
Number of limited joints -1.023 .299 -.267 .001  
Number of active joints -1.002 .496 -.156 .045  
MTX administration route -4.756 2.210 -.165 .033  
MTX current weekly dose -.572 .289 -.185 .050  
6 age .023 .317 .007 .941 .305
Number of limited joints -1.084 .287 -.283 .000  
Number of active joints -.874 .476 -.136 .068  
MTX administration route -3.892 2.126 -.135 .069  
MTX current weekly dose -.495 .277 -.160 .077  
feel sick after taking MTX -7.951 2.121 -.278 .000  
Psychosocial summary score
1 feel sick after taking MTX -5.624 1.976 -.230 .005 .053
2 feel sick after taking MTX -5.338 1.940 -.218 .007 .097
  anxious about blood tests -5.347 2.027 -.209 .009  
  1. Variables entered into the models:
  2. Block 1: age, sex.
  3. Block 2: age, sex, number of active joints, number of limited joints.
  4. Block 3: age, sex, number of active joints, number of limited joints, MTX administration route, duration of MTX use, MTX current dose.
  5. Block 4: age, sex, number of active joints, number of limited joints, MTX administration route, duration of MTX use, MTX current dose, feel sick before taking MTX, feel sick after taking MTX, vomit after taking MTX, anxious about blood tests, anxious about injections.