Profiling anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis

Table 6 prior studies of ACPA in JIA

Author (Ref)	Year	All JIA		RF-positive polyarticular JIA		Controls
Author (Ref)	Year	N	Prevalence of ACPA	N	Prevalence of ACPA	N	Prevalence of ACPA
Avcin[2]	2002	109	1.8	1	0.0	30	0.0
Hromadnikova[13]	2002	140	5.0	18	11.1	24	0.0
Van Rossum[20]	2003	71	14.1	11	72.7	-	-
Low[17]	2004	66	77.3	16	75.0	25	0.0
Kasapcopur[14]	2004	122	2.5	12	25.0	15	0.0
Kwok[16]	2005	59	10.2	5	80.0	60	0.0
Ferucci[9]	2005	230	5.7	14	57.1	688	0.6
Brunner[8]	2006	45	4.4	2	100.0	42	0.0
Kuna[15]	2009	56	1.8	2	50.0	17	0.0
Habib[12]	2008	68	20.6	20	70.0	20	0.0
Gupta[11]	2010	78	23.1	8	87.5	0	-
Morbach[21]	2010	191	2.6	6	66.7	88	1.1
Gilliam[10]	2011	96	14.6	16	56.3	10	-
Present study	2012	334	14	30	73.3	50	2.0
Total		1665	14.1	161	58.9	1069	0.33

Prior published studies that investigated prevalence of ACPA in JIA. First author, year of publication and reference number are indicated. The mean prevalence is provided in the last row for all JIA, polyarticular RF-positive JIA and controls. After excluding subjects with RF-positive polyarticular JIA, the prevalence of ACPA is 6% in JIA.

ISSN: 1546-0096