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Table 4 Association of demographic, clinical and therapeutic parameters and PROs with WHO-5, PHQ-9 and GAD-7 scores

From: Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany

 

WHO-5 score

PHQ-9 score

GAD-7 score

beta

95% CI

p value

betaST

beta

95% CI

p value

betaST

beta

95% CI

p value

betaST

Female

-4.17

-8.06; -0.28

0.036

-0.08

1.65

0.87; 2.43

< 0.001

0.17

1.52

0.79; 2.24

< 0.001

0.17

Age

-0.94

-1.89; 0.01

0.052

-0.08

0.20

0.01; 0.40

0.037

0.08

0.14

-0.04; 0.31

0.134

0.06

JIA

(ref)

   

(ref)

   

(ref)

   

SLE

3.31

-3.88; 10.50

0.367

0.04

-0.41

-1.87; 1.05

0.580

-0.02

-0.21

-1.54; 1.13

0.761

-0.01

JDM

5.13

-7.77; 18.04

0.435

0.03

-0.64

-3.41; 2.13

0.650

-0.02

-0.25

-2.84; 2.35

0.853

-0.01

PhGA

-0.78

-1.95; 0.40

0.196

-0.06

-0.11

-0.36; 0.13

0.375

-0.04

0.00

-0.23; 0.22

0.984

-0.01

MTX

-2.04

-6.01; 1.94

0.315

-0.04

0.50

-0.30; 1.29

0.223

0.05

0.64

-0.10; 1.38

0.088

0.07

bDMARD

1.76

-2.24; 5.76

0.389

0.03

0.16

-0.64; 0.96

0.692

0.02

-0.08

-0.82; 0.66

0.826

-0.01

PGA

-3.05

-3.91; -2.19

< 0.001

-0.32

0.58

0.41; 0.75

< 0.001

0.30

0.43

0.27; 0.58

< 0.001

0.24

CHAQ

-5.33

-9.91; -0.75

0.023

-0.10

1.68

0.72; 2.64

0.001

0.16

1.65

0.81; 2.50

< 0.001

0.18

  1. betaST: standardized beta coefficient; JIA: Juvenile idiopathic arthritis; SLE: Systemic lupus erythematosus; JDM: Juvenile dermatomyositis; PhGA: Physician`s global assessment of disease activity; MTX: Methotrexate; bDMARD: Biologic disease modifying antirheumatic drug; PGA: Patient`s global assessment of health status; CHAQ: Child health questionnaire