Fig. 3
From: Juvenile eosinophilic fasciitis: a single center case series
Representative eosinophilic fasciitis pathology characteristics. A Hematoxylin and eosin (H&E) section (patient 4, magnification, × 40) showing fascia with underlying muscle. The fascia shows thickening and moderate inflammatory cell infiltration. B H&E section (patient 3, magnification, × 400) showing extensive infiltration of fascia by inflammatory cells composed of lymphocytes, plasma cells, macrophages, and eosinophils. C CD45 (leukocyte common antigen, LCA) immunohistochemical stain (patient 4, magnification, × 200) highlighting the inflammatory cells. D CD163 immunohistochemical stain (patient 4, magnification, × 200) highlights macrophages. E CD138 immunohistochemical stain (patient 4, magnification, × 200), highlights plasma cells. F H&E section (patient 4, magnification, × 200) showing muscle with mild perimysial inflammation (black arrow)