Table 2 A summary of current sJIA-related studies on coronary artery damage

Gonca Keskindemirci

1

1

1

2 years

Left coronary artery dilatation(z score:3.23),Left anterior descending artery dilatation(z score:4.83)

Methotrexate,Steroid, Anakinra,Cyclosporin, Prednisolon

6 months

Shakeel Shaikh

1

1

1

6 years

right coronary artery dilatation(5.7 - 6.2 mm) with Thrombus formation

Methylprednisolone

2 weeks

Alain Lefèvre-Utile

29

4

1

10 months

Left coronary artery dilatation of 3 mm, a pericardial effusion

High doses of systemic steroids, MTX,Etanercept, Canakinumab,Roactemra

3 months

2

14 months

Pericardial effusion (5,6 mm) and hyperechogenicity with irregularity of the left coronary artery

High doses of systemic steroids

1 week for the artery dilatation and 1 month for pericarditis

3

2 years

Thickened left coronary artery walls

High doses of systemic steroids, Tocilizumab

1 week

4

14 years

a hyperechogenicity of the left and right arteries

High doses of systemic steroids, Anakinra

2 weeks

Bryce A.Binstadt

12

5

1

4 years

Left coronary artery dilatation(z score:3.19),Left anterior descending artery dilatation(z score:2.47)

Methotrexate

4 months

2

6 years

Right coronary artery dilatation(z score:3.18)

Methotrexate, Infliximab

5 Days

3

2 years

Right coronary artery dilatation(z score:2.53)

Methotrexate, Naproxen

5 Days

4

1 year

Left anterior descending artery dilatation (z score:2.2),Right coronary artery dilatation(z score:2.08)

Methotrexate, Prednisolone, Etanercept, Thalidomide, Methylprednisolone

1 month

5

10 years

Left anterior descending artery dilatation (z score:2.18)

Methotrexate, Hydroxychloroquine

1 month

Sharath Kumar

1

1

1

6 years

Right coronary artery dilatation(2.7 mm),Left coronary artery dilatation(3.3 mm),

Methylprednisolone, Cyclosporine, Etoposide,Dexamethasone

2 weeks

Li SN

5

5

1

7 months to 4 years and 7 months

Unilateral coronary artery dilation

Methylprednisolone,Methotrexate

1-3 months

2

Unilateral coronary artery dilation

Methylprednisolone,Methotrexate

3

Unilateral coronary artery dilation

Methylprednisolone, Cyclosporine,Tocilizumab,Methotrexate,

4

Bilateral coronary artery dilation

Methylprednisolone, Cyclosporine,Tocilizumab,Methotrexate,

5

Bilateral coronary artery dilation

Methylprednisolone, Cyclosporine,Tocilizumab, Methotrexate

A. Felix

25

4

1

3.8 years

Coronary artery dilation(3.6 mm)

MTX,Anakinra,Roactemra, Methylprednisolone

2 months

2

4.4 years

Coronary artery dilation(3.4 mm)

Methylprednisolone

2 months

3

7 years

Coronary artery dilation(5.2 mm)

Methylprednisolone

2 months

4

14.3 years

Coronary artery dilation(4.2 mm)

Anakinra, MethylpredNisolone

2 months