Table 3 Blood pressure and treatment in children with BD with renal artery involvement
Patient Number | Blood pressure(L/R) | RAS activation | Renal artery stenosis | Renal atrophy | Abnormal renal function (urinalysis, serum creatinine) | Markers of renal injury elevation | Glucocorticoid | Anti-hypertension drugs |
|---|---|---|---|---|---|---|---|---|
1 | L 146/116 R 144/106 | Y | Y | Y | Y | Y | MPPT(10 mg/kg.d*3days), prednisone oral(1 mg/kg) | Amlodipine(0.23 mg/kg.d) prazosin hydrochloride(0.05 mg/kg.d) |
2 | L 136/52 R 133/50 | ND | Y | Y | N | ND | MPPT(10 mg/kg.d*3days twice), prednisone oral(1 mg/kg.d) | Amlodipine(0.34 mg /kg.d) |
3 | L 128/102 R 140/108 | Y | Y | Y | N | Y | prednisone oral(1.4 mg/kg.d) | Amlodipine(0.33 mg /kg.d) Captopril(1.27 mg/kg.d) Metoprolol(1.69 mg/kg.d) |
4 | L 125/70 R 135/80 | ND | Y | N | N | Y | MPPT(10 mg/kg.d*3days ) prednisone oral(1 mg/kg.d) | Amlodipine(0.30 mg /kg.d) Captopril(1.02 mg/kg.d) |
5 | L 138/94 R148/98 | Y | Y | Y | N | Y | MPPT(10 mg/kg.d*3daystwice), prednisone oral(1 mg/kg.d) | Nifedipine nifedipine sustained-release tablet(0.6 mg/kg.d) losartan potassium(1 mg/kg.d) spironolactone(0.4 mg/kg.d) Prazosin (0.08 mg/kg.d) |
6 | L 149/97 R 154/77 | Y | Y | Y | Y | Y | MPPT(20 mg/kg.d*3days*4 times), prednisone oral (0.8 mg/kg.d) | Spironolactone(0.67 mg/kg.d) Metoprolol(0.76 mg/kg.d) Prazosin(0.05 mg/kg.d) |