|  < 18.5 N = 21 | 18.5-24.9 N = 237 | 25.0–29.9 N = 59 |  ≥ 30.0 N = 38 | P value* |
---|---|---|---|---|---|
Female, n (%) | 15(71) | 173(73) | 42(71) | 24(63) | 0.30 |
Age at onset, years, mean (SD) | 4.0(3.2) | 6.1(4.1) | 7.8(3.8) | 7.9(3.9) |  < 0.001 |
Symptom duration, months, mean (SD) | 8(16) | 5(8) | 7(9) | 5(7) | 0.95 |
ISO-BMI at onset, (z-score) mean (SD) | -1.51(3.69) | 1.08(3.24) | 2.39(2.93) | 3.10(2.32) |  < 0.001 |
JADAS at onset | 2.2(3.6) | 2.0(3.6) | 1.9(3.3) | 2.0(2.8) | 0.80 |
Age | 20.8(4.0) | 22.9(4.4) | 24.7(4.2) | 25.2(4.3) |  < 0.001 |
Disease duration | 16.5(2.9) | 16.7(1.6) | 16.6(1.4) | 17.1(1.0) | 0.24 |
Subgroup of JIA, n (%) | Â | Â | Â | Â | 0.014 |
 Persistent oligoarthritis | 9(43) | 66(28) | 10(17) | 6(16) |  |
 Extended oligoarthritis | 3(14) | 58(24) | 10(17) | 4(11) |  |
 Polyarthritis, RF-positive | 1(5) | 2(1) | 1(2) | 2(5) |  |
 Polyarthritis, RF-negative | 5(24) | 42(18) | 10(17) | 4(11) |  |
 Psoriatic arthritis | 1(5) | 7(3) | 4(7) | 6(16) |  |
 Enthesitis-related | 0(0) | 21(9) | 8(14) | 6(16) |  |
 Systemic onset | 0(0) | 11(5) | 2(3) | 0(0) |  |
 Undifferentiated | 2(10) | 30(13) | 14(24) | 10(26) |  |
DAS28 | 1.92(0.97) | 1.83(0.86) | 1.91(0.97) | 2.26(1.01) | 0.028 |
 Tender joints 28 | 1.3(2.0) | 0.6(1.7) | 0.9(2.1) | 1.9(4.3) | 0.019 |
 Swollen joints 28 | 0.5(0.7) | 0.3(1.1) | 0.5(1.5) | 0.3(1.2) | 0.92 |
 Patients’ global, VAS | 20.5(24.5) | 14.7(22.7) | 26.2(29.9) | 29.3(33.8) |  < 0.001 |
 ESR | 5.5(4.8) | 6.7(6.8) | 7.6(6.7) | 12.3(9.6) |  < 0.001 |
 CRP | 3.8(2.5) | 2.8(3.7) | 3.7(3.9) | 7.2(8.3) |  < 0.001 |
HAQ | 0.15(0.35) | 0.13(0.31) | 0.33(0.59) | 0.38(0.65) |  < 0.001 |
Remission | Â | Â | Â | Â | 0.17 |
 No remission | 14(67) | 110(46) | 24(41) | 21(55) |  |
 Remission on medication | 0(0) | 26(11) | 3(5) | 4(11) |  |
 Remission off medication | 7(33) | 101(43) | 32(54) | 13(34) |  |
Pain, VAS | 26.0(27.8) | 15.8(22.0) | 24.5(27.7) | 28.1(29.9) | 0.013 |
Fatigue total, mean (SD) | 3.0(1.6) | 3.1(1.5) | 3.5(1.7) | 3.6(1.6) | 0.035 |
PSQI, mean (SD) | 5.4(2.7) | 5.5(3.4) | 6.0(4.1) | 6.8(4.1) | 0.044 |
Kasari FIT-index | 29.0(20.9) | 33.9(23.2) | 35.5(21.8) | 28.8(19.2) | 0.68 |
Abdominal pain |  |  |  |  |  < 0.001 |
 No | 17(81) | 197(83) | 42(71) | 24(63) |  |
 Sometimes | 3(14) | 25(11) | 8(14) | 3(8) |  |
 Always | 1(5) | 15(6) | 9(15) | 11(29) |  |
Comorbidities | |||||
 Hypothyreosis | 0(0) | 6(3) | 2(3) | 0(0) | 0.78 |
 IBD | 2(10) | 7(3) | 1(2) | 1(3) | 0.30 |
Social status | Â | Â | Â | Â | 0.004 |
 Student | 10(48) | 119(50) | 27(46) | 9(24) |  |
 Employed | 6(29) | 108(46) | 29(49) | 22(58) |  |
 Unemployed | 3(14) | 5(2) | 1(2) | 1(3) |  |
 On pension | 2(10) | 5(2) | 2(3) | 6(16) |  |