Fig. 3
From: Prospective study to characterize adalimumab exposure in pediatric patients with rheumatic diseases
Adalimumab exposure in children with PRD with and without methotrexate co-treatment depending on sample time. Legend: Adalimumab exposure in children with PRD treated with adalimumab and methotrexate (A-M) and adalimumab alone (A) after ≥ 12 weeks. Maximal adalimumab concentrations were collected after 1 to 9 days (Cmax) and minimal concentrations (Cmin) after 10 to 14 days. The dash blue lines represent the interquartile ranges [IQR] and the median concentrations per study group (A-M: 15.6 mg/L [IQR 10.1, 22.3]; A: 12.3 mg/L [IQR 7.4, 16.6])