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Table 1 MAS Remission Criteria

From: The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study

MAS Remission Criteria:

Resolution of MAS clinical signs and symptoms present at baseline:

  ∙ MAS was considered resolved if VAS ≤1/10

And

Normalization of laboratory parameters relevant to MAS:

  ∙ WBC >LLN

  ∙ Platelet count >LLN

  ∙ LDH <1.5 ULN

  ∙ ALT <1.5 ULN

  ∙ AST <1.5 ULN

  ∙ Fibrinogen >100 mg/dL

  ∙ Ferritin ≤80% from values at screening or baseline (whichever is higher) or <2000 ng/mL, whichever is lower