MAS Remission Criteria: |
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✓ Resolution of MAS clinical signs and symptoms present at baseline: |
∙ MAS was considered resolved if VAS ≤1/10 |
And |
✓ Normalization of laboratory parameters relevant to MAS: |
∙ WBC >LLN |
∙ Platelet count >LLN |
∙ LDH <1.5 ULN |
∙ ALT <1.5 ULN |
∙ AST <1.5 ULN |
∙ Fibrinogen >100 mg/dL |
∙ Ferritin ≤80% from values at screening or baseline (whichever is higher) or <2000 ng/mL, whichever is lower |