Table 1 Characteristic of patients with KD initially presenting as retropharyngeal abnormality and retropharyngeal abscess without KD
Characteristic | Group A (n = 10) | Group B (n = 20) | Group C (n = 16) | P value | |
|---|---|---|---|---|---|
A vs. B | A vs. C | ||||
1. Gender | |||||
 Male | 5 (50.00%) | 12 (60.00%) | 9 (56.25%) | 0.461 | 0.756 |
 Female | 5 (50.00%) | 8 (40.00%) | 7 (43.75%) | ||
2. Age (months) | 65.80 (50.43–81.17) | 31.75 (23.31–40.19) | 56.69 (41.61–71.77) | 0.000 | 0.392 |
3. Clinical symptoms and signsa | |||||
 Fever | 9 (90.00%) | 20 (100.00%) | 14 (87.50%) | 0.333 | 1.000 |
 Cough | 1 (10.00%) | 6 (30.00%) | 1 (6.25%) | 0.372 | 1.000 |
 Nasal congestion | 1 (10.00%) | 5 (25.00%) | 2 (12.50%) | 0.633 | 1.000 |
 Neck pain | 10 (100.00%) | 5 (25.00%) | 16 (100.00%) | 0.000 | 1.000 |
 Restricted neck movements | 10 (100.00%) | 5 (25.00%) | 15 (93.75%) | 0.000 | 1.000 |
 Pharyngalgia | 7 (70.00%) | 4 (20.00%) | 15 (93.75%) | 0.015 | 0.264 |
 Pain on swallowing | 6 (60.00%) | 0 | 11 (68.75%) | 0.000 | 0.692 |
 Pharyngeal congestion | 8 (80.00%) | 13 (65.00%) | 14 (87.50%) | 0.675 | 0.625 |
 Swollen tonsils | 6 (60.00%) | 2 (10.00%) | 13 (81.25%) | 0.007 | 0.369 |
 Lymphadenitis | 10 (100.00%) | 4 (20.00%) | 10 (100.00%) | 0.000 | 1.000 |
 Rash | 0 | 18 (90.00%) | 0 | 0.000 | 1.000 |
Nonpurulent conjunctivitis | 0 | 17 (85.00%) | 0 | 0.000 | 1.000 |
 Cracked lips | 0 | 19 (95.00%) | 0 | 0.000 | 1.000 |
 Extremitiesb | 0 | 11 (55.00%) | 0 | 0.0004 | 1.000 |
 Hoarseness | 2 (20.00%) | 3 (15.00%) | 2 (12.50%) | 1.000 | 0.625 |
4. Fever—highest (°C) | 39.76 (39.33–40.19) | 39.86 (39.63–40.08) | 38.73 (38.20–39.28) | 0.643 | 0.008 |
5. Fever duration (day) | |||||
  Before antibiotic therapy | 2.50 (1.37–3.63) | 5.00 (3.47–6.53) | 4.19 (1.47–6.91) | 0.005 | 0.670 |
 After antibiotic therapy | 4.50 (3.42–5.58) | 2.10 (1.60–2.60) | 1.31 (0.57–2.06) | 0.000 | 0.000 |
 As a whole | 7.00 (5.42–8.58) | 7.15 (5.72–8.58) | 5.43 (2.53–8.34) | 0.530 | 0.071 |
6. Fever duration after antibiotic therapy (day) | |||||
  < 3 | 1 (10.00%) | 9 (45.00%) | 13 (81.25%) | 0.024 | 0.001 |
  ≥ 3 | 9 (90.00%) | 11 (55.00%) | 3 (18.75%) | ||
7. Laboratory parametersa | |||||
 WBC (×109/L) | 16.35 (12.13–20.56) | 14.94 (13.00–16.87) | 20.81 (17.31–24.31) | 0.567 | 0.040 |
 Reticulocyte (× 1012/L) | 4.33 (4.01–4.65) | 4.16 (3.99–4.33) | 4.39 (4.10–4.68) | 0.692 | 0.768 |
 Haemoglobin (g/L) | 116.30 (110.71–121.89) | 111.55 (106.91–116.19) | 115.81 (109.19–122.43) | 0.198 | 0.913 |
 Platelet (× 109/L) | 352.00 (313.98–390.02) | 326.65 (263.90–389.40) | 411.63 (341.44–481.81) | 0.572 | 0.246 |
 CRP (mg/L) | 94.19 (78.68–109.69) | 51.89 (34.75–69.02) | 58.14 (38.33–77.96) | 0.002 | 0.011 |
 ESR (mm/h) | 63.90 (46.35–81.45) | 55.20 (48.16–62.24) | 65.88 (54.99–76.76) | 0.509 | 0.826 |
 Procalcitonin (ng/mL) | 1.25(−0.22–2.72) | 2.78(− 0.11–5.67) | 0.47 (0.22–0.72) | 0.895 | 0.812 |
 Total protein (g/L) | 73.62 (70.72–76.52) | 62.89 (60.66–65.11) | 74.63 (71.65–77.62) | 0.000 | 0.626 |
 Albumin (g/L) | 38.86 (36.72–41.00) | 36.05 (34.86–37.23) | 38.46 (36.63–40.29) | 0.012 | 0.763 |
 Globulin (g/L) | 34.76 (32.62–36.89) | 26.84 (24.94–28.74) | 35.86 (32.58–39.13) | 0.000 | 0.605 |
 ALT (IU/L) | 91.00 (15.04–166.94) | 104.00 (50.83–157.17) | 13.75 (10.07–17.43) | 0.676 | 0.002 |
 AST (IU/L) | 65.60 (28.89–102.31) | 70.10 (20.32–119.88) | 25.25 (20.50–30.00) | 0.692 | 0.013 |
 Total bilirubin (μmol/L) | 14.81 (0.76–30.38) | 14.47 (6.10–22.85) | 8.18 (4.62–11.93) | 0.650 | 0.623 |
 Direct bilirubin (μmol/L) | 9.57 (2.87–22.01) | 8.91 (2.70–15.11) | 3.66 (2.07–5.26) | 0.914 | 0.262 |
 Alkaline phosphatase (IU/L) | 187.60 (153.79–221.41) | 203.15 (162.82–243.48) | 183.88 (162.83–204.92) | 0.843 | 0.830 |
 γ-glutamyl transpeptidase (IU/L) | 46.10 (6.20–86.00) | 83.15 (48.60–117.70) | 17.56 (12.59–22.53) | 0.134 | 0.427 |
 Na (mmol/L) | 134.13 (131.54–136.72) | 135.08 (133.87–136.29) | 135.39 (133.98–136.80) | 0.414 | 0.317 |
 APTT (S) | 41.05 (33.88–48.22) | 36.25 (32.68–39.81) | 37.13 (32.36–41.89) | 0.194 | 0.309 |
 PT (S) | 14.31 (13.48–15.14) | 13.69 (13.14–14.24) | 13.12 (11.31–14.93) | 0.178 | 0.225 |
 NT-proBNP (ng/L)d | 247.62 (174.18–321.06) | 175.19 (15.91–334.46) | – | 0.267 | – |
 Ferritin (μg/L) | 489.74 (1.22–980.71) | 259.93 (184.15–335.70) | – | 0.377 | – |
 Troponin I (×10−3 μg/L) | 1.9 (0.45–3.35) | 4.35 (1.15–9.85) | 0.50 (0.06–0.94) | 0.681 | 0.020 |
8. Radiological findings | |||||
 Ring enhancementc | 0 | – | 11 (100.00%) | – | 0.000 |
 CT Number of RA | 21.70 (16.53–26.87) | – | 23.50 (17.60–29.40) | – | 0.653 |
9. Hospital length of stay (day) | 11.10 (9.37–12.83) | 6.70 (5.32–8.08) | 8.56 (6.51–10.61) | 0.000 | 0.075 |