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Table 1 Baseline data of 25 children

From: Kawasaki disease complicated by peripheral artery thrombosis: a case report and literature review

References

Sex/Age (month)

Incomplete KD

Coronary artery lesions

IVIG

Corticosteroids treatment

Immunosuppressive and biological agentsb

Peripheral gangrene site

Abnormal timing of peripheral gangrene

Recovery time from peripheral gangrene

Prognosis of peripheral gangrene

Anticoagulation, thrombolytic and other therapy (Besides aspirin)a

Fatemeh Tahghighi et al.

F/8

–

Dilatation

(+)/2 doses

(+)

NA

Knee

26th

56th

No significant sequelae

–

Iran Malekzadeh et al.

M/4

Incomplete

Multiple aneurysms

(+)

(+)

2

On both sides lower and right fingers

NA

–

Amputation

1

F/6

Incomplete

Dilatation

(+)

(+)

NA

Right fingers

NA

NA

No significant sequelae

NA

M/12

Incomplete

Multiple aneurysms

(+)/2 doses

(+)

1,4

Fingers

20th

NA

No significant sequelae

1,2

M. von Planta et al.

F/2

incomplete

Multiple aneurysms

(+)

NA

NA

Left fingers, right toes

18th

40th

No significant sequelae

1,3

Na Yeon Kim et al.

M/57d

–

Multiple aneurysms

(+)/4 doses

(+)

3

Left fingers, right toes

14th

22nd

No significant sequelae

1,2

Jai Prakash Son et al.

M/4Y

incomplete

Normal

(+)

NA

NA

Left side of the lower lip and left finger

7th

NA

No significant sequelae

1

Matthew J.O’Connor et al.

M/7 weeks

incomplete

Multiple aneurysms

(+)/2 doses

(+)

NA

Left toes and the left finger

8th

NA

NA

1,4

A. L. Durall et al.

M/1

–

Multiple aneurysms

(+)/2 doses

(+)

NA

Hands and feet

14th

–

Amputation

1,4,8

Faten Al Tasseh et al.

M/ 14

incomplete

Dilatation

(+)

(+)

NA

right fingers

9th

–

Amputation

1,3,5

Shobun Tomita et al.

F/ 2

incomplete

Multiple aneurysms and Coronary artery thrombosis

(+)/2 doses

NA

NA

Left fingers

22th

23rd, Partial improvement

Partial amputation

1,2,3,4,6,7

M/2

incomplete

Multiple aneurysms

(+)

NA

NA

The left hand

17th

22nd, Partial improvement

Partial amputation

1,2

F/3

–

Multiple aneurysms

(+)/3 doses

(+)

NA

left hand (at the wrist), left leg (at the knee), and

18th

–

Amputation

1

right foot (at the ankle)

C. Krohn et al.

F/3

Incomplete

Aneurysms

(+)

(+)

NA

The left hand and left foot

28th

–

Amputation

1,6

Mark A. Westphalen et al.

M/5

–

Aneurysms

(+)

(+)

NA

Hands

18th

28th, Most improvement

Partly leaving after-effects

3,4

Elisabeth Gomez Moyano et al.

M/4

–

Multiple aneurysms

(+)

(+)

NA

Fingers and toes

15th

–

Amputation

1,3,4

Elliot L. Ames et al.

M/4

–

Multiple aneurysms

NA

NA

NA

Hands

27th

–

Amputation

1

O H Teixeira et al.

F/7

–

Multiple aneurysms

NA

NA

NA

Fingers and toes

16th

70th, Most improvement

NA

NA

Omer Faruk Dogan et al.

F/7Y

–

Multiple aneurysms

(+)

(+)

NA

Left toes

6th

21st

No significant sequelae

1,3

Muhammad Mohsin et al.

F/10

–

Dilatation

(+)

NA

NA

Left big toe

7th

10th, Most improvement

No significant sequelae

1,4

J.-S. Chang et al.

M/8.5

–

Dilatation and Aneurysms

(+)

NA

NA

Fingers and toes

7th

23th, Most improvement

Partial amputation

1

J L Brenner et al.

F/3

Incomplete

Dilatation and Aneurysms

NA

NA

NA

Right toes

41th

–

Amputation

NA

M/5

–

Multiple aneurysms

(+)/3 doses

(+)

NA

Big toe

28th

NA

NA

1,2,4,6

Garrido-García LM, et al.

F/45d

NA

NA

NA

NA

NA

Right toes

NA

NA

NA

NA

Madan D et al.

M/3.5Y

Incomplete

Dilatation

(+)/2 doses

(+)

4

Both hands and feet and face

5th

NA

No significant sequelae

1

  1. a1. Heparin, 2. Warfarin, 3. Prostaglandin, 4. Nitroglycerin, 5. Fresh frozen plasma, 6. tissue type PA(t-PA), 7. Urokinase, 8. antithrombin III
  2. b1. Azathioprine; 2. Cyclophosphamide; 3. Methotrexate; 4. Infliximab