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Table 1 The symptoms and features of the children with multisystem inflammatory syndrome in children

From: A retrospective comparative analysis of factors affecting the decision and outcome of initial intravenous immunoglobulin alone or intravenous immunoglobulin plus methylprednisolone use in children with the multisystem inflammatory syndrome

Presenting symptoms

Group I (IVIG alone) (%)

Group II (IVIG plus steroid) (%)

Total Number (%)

P value

Fever

42(100)

49 (100)

91(100)

 

Cough

8(19.0%)

2 (4.1%)

10 (11.0)

0.04

Abdominal pain

13(31.0)

19(38.8)

32(35.2)

 > 0.05

Chest pain

1(2.4)

2(4.1)

3(3.3)

 > 0.05

Vomitting

11(26.2)

22(44.9)

33(36.3)

 > 0.05

Diarrhea

10(23.8)

17(34.7)

27(29.7)

 > 0.05

Rash

11(26.2)

17(34.7)

28(30.8)

 > 0.05

Edema of the extremities

6(14.3)

8(16.3)

14 (15.4)

 > 0.05

Periungal desquamation

5(11.9)

2(4.1)

7(7.7)

NA

Conjuctivitis

12 (28.6)

17 (34.7)

29(31.9)

 > 0.05

Headache

1 (2.4)

4(8.3)

5(5.5)

NA

Cervical Lympadenopathy

4(9.5)

4(8.2)

8(8.8)

NA

Clinical evaluation

    

 Hypotension

4(9.5)

15 (30.6)

19(20.9)

0.014

 Tachycardia

10 (23.8)

10 (20.4)

20(22.0)

 > 0.05

 Tachypnea

4(9.5%)

4 (8.2)

8(8.8)

 > 0.05

 Echo findings

    

Systolic dysfunction

3(7.1)

7(14.3)

10(11)

 > 0.05

 Coronary artery involvement

4(9.5)

1(2.0)

5(5.5)

NA

 Pericardial effusion

-

1(2.0)

1(1.1)

NA

 Mitral valve regurgitation

15(35.7)

18(36.7)

33(36.2)

 > 0.05

Severity score

   

0.01*

 Mild

28(66.7)

23 (46.9)

51(56.0)

 

 Moderate

10( 23.8)

8 (16.3)

18 (19.8)

 

 Severe

4(9.5)

18(36.7)

22(24.2)

 

 Admission to PICU

6 (14.3)

16(32.7)

22(24.2)

0.032

  1. aThe ratio of severe MIS-C patients in the group II was 36.7% (n = 18) and significantly higher compared to the rate of severe MIS-C patients in the group I (n = 4, 9.5%) (p = 0.01)
  2. NA Not applicable, PICU Pediatric Intensive Care Unit