Fig. 1
From: H syndrome: 5 new cases from the United States with novel features and responses to therapy
Patient 1 Skin Biopsy. a: The dermis contains scattered interstitial histiocytes and a few background eosinophils and mast cells. (10X) b: Higher magnification showing a histiocytic infiltration in the dermis. These histiocytes stain positive for CD68, factor XIIIa, Ham56, and S100P (subset) but negative for CD1a. (20X) c: The overlying epidermis is not involved. No hyperpigmentation is appreciated. (20X)