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Table 5 (abstract P184). Characteristics of pediatric patients with early-onset systemic lupus erythematosus

From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

 

Pt 1

Pt 2

Pt 3

Pt 4

Pt 5

Pt 6

Pt 7

SLE in sibling

+

+

-

-

+

-

+

Mutant genes

C1QA

C1QC

C1QC

C1QA

C1S

DNASE1L3

Novel gene (?)

Malar/discoid rash/photosensitivity

+

+

+

+

+

+

-

Oral ulcers

+

+

+

-

+

-

-

Arthritis

+

+

-

-

+

+

-

Nephritis

-

-

-

-

+

+

-

Hematologic involvement

+

+

+

-

+

+

-

Decrease in C3, C4

-

-

-

-

+

+

+

Autoantibodies*

Anti-SM

RF

Anti-SM, anti-SSA, LA

Anti-SM, U1RNP

AntidsDNA, Anti-SSA, U1RNP, anti-histon

AntidsDNA, Anti-CL

AntidsDNA, DC

  1. Pt patients, SLE systemic lupus erythematosus, CL cardiolipin, LA lupus anticoagulant, RF rheumatoid factor
  2. * ANA was positive in all patients