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Table 23 (abstract P272). Patient characteristics and pregnancy characteristics

From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

 

cSLE:

n = 101

SLE

n = 37

p*

Ethnicity

   

White

71%

68%

 

Non White (%)

29%

32%

 

Age at study visit (median (range))

33 (18 – 65)*

38 (25 – 76)*

0.003

Age at diagnosis in yrs (median (range))

14 (5 – 17)*

26 (18 – 63)*

0.000

Disease duration in yrs (median (range))

20 (1 – 55)

12 (1 – 34)

0.000

Current SLEDAI-2 K score (median (range))

4 (0 – 14)

5 (0 – 10)

 

SDI-score (median (range))

1 (0 – 8)

1 (0 – 7)

 

Patients with SLICC-DI ≥ 1

60% (61/40)

57% (21/37)

 

cSLE restrictive in pregnancy wish

66% (63/96)

69% (25/36)

 

Patients ever pregnant (after diagnosis of SLE)

36% (36/101)

41% (9/22)

 

With history of cyclophosphamide use

22% (8/36)

22% (2/9)

 

Time to first pregnancy, months (median(range))

2 (0 – 84)

1 (0 – 12)

n.s.

Age at first pregnancy, yrs (median(range))

27 (18 – 36)

30 (22 – 32)

n.s.

Total number of pregnancies

85

19

 

Miscarriages (<20 weeks)

15% (13/85)

21% (4/19)

 

Induced Abortion

6% (5/85)

0

 

Any pregnancy complications > 20 weeks

37% (25/67)

27% (4/15)

n.s.

Stillbirth

16% (4/25)

0

Pregnancy induced hypertension

12% (3/25)

0

Pre-eclampsia/HELLP

24% (6/25)

0

Preterm birth (AD < 37 weeks)

20% (5/25)

25% (1/4)

Median gestational age (range)

31 wk,28-35

32 wk

Placental abruption

8% (2/25)

25% (1/4)

Other

20% (5/25)

50% (2/4)

  1. if no p-values are given, differences between cSLE and SLE were not statistically significant