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Table 17 (abstract P234). Characteristics of patients who received live-attenuated vaccines

From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

Patient

Disease

Biological

Other medication

Vaccination

Adverse events

Flare

1

CINCA

Anakinra

1.5 mg/kg/day

Methyl-prednisolone

MMR booster

-

-

2

MKD

Anakinra 1.4 mg/kg/day

-

MMR booster

-

-

3

FMF

Canakinumab 4 mg/kg/monthly

Prednisone

Colchicine

MMR booster

-

FMF attack after 1 week

4

sJIA

Canakinumab

4 mg/kg/2 months

Prednisone

Methotrexate

Ibuprofen (if necessary)

MMR booster

Pneumonia 1 week after vaccination

Fever and rash attacks

5

sJIA

Anakinra 1.7 mg/kg/2 days

Methotrexate Indometacine

MMR booster

-

A bit more exanthema due to stop of anakinra

6

sJIA

Anakinra 40 mg/3 days

-

MMR booster

-

-

7

sJIA

Tocilizumab 132 mg/14 days

Prednisone

Indometacine

Varicella zoster (first vaccine)

-

Exanthema,

subfebrile temperature, malaise

8

sJIA

Anakinra 4 mg/kg/day

Prednisone

Methotrexate

Leflunomide

Thalidomide

Varicella zoster (booster)

Hospitalization due to varicella infection and immune-suppression, treatment with acyclovir

-

9

sJIA

Tocilizumab

12 mg/kg/monthly

Prednisone

Ibuprofen (if necessary)

Oral polio vaccine

Diarrhea

-