Fig. 1

Historical Juvenile Spondyloarthropathy Concept. References: JAS: Juvenile Ankylosing spondylitis; PsA: Psoriatic arthritis; ReA: Recative arthritis; IBD:inflammatory bowel disease. SEAS:Seronegative enthesitis and arthritis syndrome; ERA (ILAR Criteria) Enthesitis_related arthritis: arthritis and enthesitis or arthritis or enthesitis with at least two of the following: sacroiliac joint tenderness and/or inflammatory spinal pain; presence of HLA-B27, family history in at least one first-degree relative with medically confirmed HLA-B27 associated disease, anterior uveitis that is usually associated with pain, redness, or photophobia, onset of arthritis in a boy after 6 years of age. Exclusions: psoriasis confirmed by a dermatologist in at least one first- degree relative, presence of systemic arthritis