Table
From: Primary angiitis of the central nervous system in children - case series
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
Age at onset (years) | 13 | 1,5 | 12 | 16 | 5,5 | 6 | 15 |
Time to diagnosis (months) | 30 | 5 | 1 | 1,5 | 12 | 1 | 1,5 |
F/U (years) | 4 | 13 | 5 | 0,5 | 2 | 1,5 | 1 |
Manifestation at onset | generalised seizures | focal seizure, stroke | seizure sensory deficit | sensory deficit, stroke | stroke | stroke with ataxia | seizures stroke |
MRI at onset | UL, MF | UL, MF | BL, MF | BL,MF | UL,MF | UL, F | UL,MF |
Angiography at onset | N/D | posit. | posit. | posit. | posit. | posit. | neg. |
Initial therapy | AED | AED | ACA | ACA, CS | 0 | ACA | IVMP, AED |
Manifestation at F/U | seizures cognitive dysfunction | hemiparesis developmental delay | normal | normal | cognitive dysfunction, hemiparesis | normal | organic psychosis |
MRI at F/U | BL, MF | N/D | N/D | N/D | BL, MF | regression | BL, MF |
Angiography F/U | neg. | N/D | N/D | N/D | regression | regression | neg. |
Therapy at F/U | AED, CS | AED, ACA | ACA | CS | ACA | ACA | CYC, CS |