Figure 4From: Joint contractures in the absence of inflammation may indicate mucopolysaccharidosisCorneal Clouding in Patients with MPS I. Corneal clouding is an early and almost universal sign of MPS I in both severe and attenuated phenotypes. It can be very marked, as in the right eye of the patient shown in the upper panel, or less obvious as in the eye shown in the lower panel. Typically, it is bilateral; in the patient shown in the upper panel, a corneal transplant was performed in the left eye. Photos courtesy of J. Edmond Wraith.Back to article page