Table 1 Associations between JIA subtypes and different HLA alleles.
From: A comprehensive review of the genetics of juvenile idiopathic arthritis
Phenotype | Alleles conferring susceptibility | Protective alleles |
|---|---|---|
Oligoarticular | A2, DRB1*01, DRB1*08, DRB1*11, DRB1*13, DPB1*02, DQA1*04, DQB1*04 | DRB1*04, DRB1*07, DQA1*03 |
Polyarticular RF+ | DRB1*04, DQA1*03, DQB1*03 | DQA1*02 |
Polyarticular RF- | A2, DRB1*08, DQA1*04, DPB1*03 | Â |
Psoriatic | DRB1*01, DQA1*0101 | DRB1*04, DQA1*03 |
ERA | B27, DRB1*01, DQA1*0101, DQB1*05 | Â |
Systemic | DRB1*04, DRB1*11, DQA1*05 | Â |