Figure 2From: Development of positive antinuclear antibodies and rheumatoid factor in systemic juvenile idiopathic arthritis points toward an autoimmune phenotype later in the disease courseConcept schematic of the different disease courses of systemic juvenile idiopathic arthritis. The lower curve shows the postulated two phases of persistent disease course, with initially predominant systemic disease and development of chronic polyarthritis later in the disease course.Back to article page