Table 4 Meta-analysis results for PTPN22, MIF and TNFA variants and JIA

PTPN22 C1858T

All Studies

3261

0.14

4982

0.11

1.44 (1.31, 1.60)

<0.0001

4-7, 18,19, 29

MIF G-173C

Including Donn et al. [16]

1382

0.19

1544

0.17

1.26 (1.09, 1.45)

0.0356

9, 13, 16

Removing Donn et al.

856

0.19

1285

0.18

1.12 (0.96, 1.32)

0.1548

TNFA G-238A

Including Ozen et al. [22]

1399

0.07

1648

0.07

0.84 (0.68, 1.04)

0.1033

9, 11, 20, 22, 23

Removing Ozen et al.

1189

0.03

1455

0.04

0.69 (0.52, 0.91)

0.0086

TNFA G-308A

Including Ozen et al. [22]

1583

0.17

1952

0.16

1.01 (0.88, 1.15)

0.925

9, 11, 12, 20-23

Removing Ozen et al.

1373

0.15

1759

0.16

0.95 (0.83, 1.10)

0.5137