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  1. Autoimmunity is often observed among individuals with primary immune deficiencies; however, the frequency and role of autoimmunity in Schimke immuno-osseous dysplasia (SIOD) has not been fully assessed. SIOD, ...

    Authors: Jakub Zieg, Anna Krepelova, Alireza Baradaran-Heravi, Elena Levtchenko, Encarna Guillén-Navarro, Miroslava Balascakova, Martina Sukova, Tomas Seeman, Jiri Dusek, Nadezda Simankova, Tomas Rosik, Sylva Skalova, Jan Lebl and Cornelius F Boerkoel
    Citation: Pediatric Rheumatology 2011 9:27
  2. Although musculoskeletal ultrasound (MSUS) has emerged as an indispensible tool among physicians involved in musculoskeletal medicine in the last two decades, only recently has it become more attractive to ped...

    Authors: Fatih Tok, Erkan Demirkaya and Levent Özçakar
    Citation: Pediatric Rheumatology 2011 9:25
  3. The presence of enthesitis (insertional inflammation) in patients with juvenile idiopathic arthritis (JIA) is difficult to establish clinically and may influence classification and treatment of the disease. We...

    Authors: Louise Laurell, Michel Court-Payen, Susan Nielsen, Marek Zak, Carsten Thomsen, Maribel Miguel-Pérez and Anders Fasth
    Citation: Pediatric Rheumatology 2011 9:22
  4. We present the case of an 11-year-old boy presenting with haemoptysis, dyspnoea and weight loss as a manifestation of isolated pulmonary vasculitis, leading to pulmonary hypertension. He also appeared to have ...

    Authors: Willemien de Vries, Gerard H Koppelman, Marc TR Roofthooft, Hendrika Bootsma, Martha K Leijsma and Wineke Armbrust
    Citation: Pediatric Rheumatology 2011 9:19
  5. Linear scleroderma is a form of localized scleroderma that primarily affects the pediatric population. When it occurs on the scalp or forehead, it is termed "en coup de sabre". In the en coup de sabre subtype,...

    Authors: Emily T Fain, Melissa Mannion, Elena Pope, Daniel W Young, Ronald M Laxer and Randy Q Cron
    Citation: Pediatric Rheumatology 2011 9:18
  6. Systemic juvenile idiopathic arthritis (sJIA) is a systemic inflammatory disease characterized by arthritis, spiking fever and a skin rash that is frequently complicated by macrophage activation syndrome (MAS)...

    Authors: Tomonari Shigemura, Takashi Yamazaki, Yosuke Hara, Jing-Ni Ou, Anne M Stevens, Hans D Ochs, Kenichi Koike and Kazunaga Agematsu
    Citation: Pediatric Rheumatology 2011 9:15
  7. Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare and severe hereditary skin disease. Oligoarticular Juvenile Idiopathic Arthritis (JIA) although infrequent in the general paediatric population, is t...

    Authors: Despoina Maritsi, Anna E Martinez, Jemima E Mellerio, Despina Eleftheriou and Clarissa A Pilkington
    Citation: Pediatric Rheumatology 2011 9:13
  8. Primary systemic vasculitis presenting in childhood is an uncommon but serious condition. As these patients transfer to adult clinics for continuing care, defining long term outcomes with emphasis on disease a...

    Authors: Nishkantha Arulkumaran, Susan Jawad, Stuart W Smith, Lorraine Harper, Paul Brogan, Charles D Pusey and Alan D Salama
    Citation: Pediatric Rheumatology 2011 9:12
  9. Children with complex medical issues experience barriers to the transition of care from pediatric to adult providers. We sought to identify these barriers by elucidating the experiences of patients with idiopa...

    Authors: James D Katz, Gulnara Mamyrova, Shilpi Agarwal, Olcay Y Jones, Harriet Bollar, Adam M Huber, Lisa G Rider and Patience H White
    Citation: Pediatric Rheumatology 2011 9:10
  10. Although electronic medical records (EMRs) have facilitated care for children with juvenile idiopathic arthritis (JIA), analyses of treatment outcomes have required paper based or manually re-entered data. We ...

    Authors: Michael L Miller, Jason Ruprecht, Deli Wang, Ying Zhou, George Lales, Sean McKenna and Marisa Klein-Gitelman
    Citation: Pediatric Rheumatology 2011 9:9
  11. Several studies have noted the significance of measuring anti-cyclic citrullinated peptide (CCP) antibodies in juvenile idiopathic arthritis (JIA) as an important indicator for destructive disease, as is the c...

    Authors: Brooke E Gilliam, Melinda R Reed, Anil K Chauhan, Amanda B Dehlendorf and Terry L Moore
    Citation: Pediatric Rheumatology 2011 9:8
  12. Spinal epidural lipomatosis is a rare complication of chronic corticosteroid treatment. We report a new pediatric case and an analysis of this and 19 pediatric cases identified in the international literature....

    Authors: Jana C Möller, Randy Q Cron, Daniel W Young, Hermann J Girschick, Deborah M Levy, David D Sherry, Akiko Kukita, Kaoru Saijo and Frank Pessler
    Citation: Pediatric Rheumatology 2011 9:5
  13. The ankle region is frequently involved in juvenile idiopathic arthritis (JIA) but difficult to examine clinically due to its anatomical complexity. The aim of the study was to evaluate the role of ultrasonogr...

    Authors: Louise Laurell, Michel Court-Payen, Susan Nielsen, Marek Zak, Mikael Boesen and Anders Fasth
    Citation: Pediatric Rheumatology 2011 9:4
  14. Chronic non-specific musculoskeletal pain (CNSMSP) may develop in childhood and adolescence, leading to disability and reduced quality of life that continues into adulthood. The purpose of the study was to bui...

    Authors: Peter O'Sullivan, Darren Beales, Lynn Jensen, Kevin Murray and Tenielle Myers
    Citation: Pediatric Rheumatology 2011 9:3
  15. The glucocorticoid receptor gene (NR3C1) has been suggested as a candidate gene affecting juvenile idiopathic arthritis (JIA) course and prognosis. The purpose of this study is to investigate the glucocorticoi...

    Authors: Mikhail M Kostik, Alexandra A Klyushina, Mikhail V Moskalenko, Larisa A Scheplyagina and Valentina I Larionova
    Citation: Pediatric Rheumatology 2011 9:2
  16. Autoimmune pancreatitis is frequently associated with elevated serum and tissue IgG4 levels in the adult population, but there are few reports of pediatric autoimmune pancreatitis, and even fewer reports of Ig...

    Authors: Melissa Mannion and Randy Q Cron
    Citation: Pediatric Rheumatology 2011 9:1
  17. The clinical relevance of observations of serum levels of osteoprotegerin (OPG) and receptor activator of nuclear factor -κB ligand (RANKL) in juvenile idiopathic arthritis (JIA) is not clear. To elucidate the...

    Authors: Gunhild Lien, Thor Ueland, Kristin Godang, Anne M Selvaag, Øystein T Førre and Berit Flatø
    Citation: Pediatric Rheumatology 2010 8:30
  18. To analyze the prevalence of diagnosed and suspected autoinflammatory diseases in Eastern and Central European (ECE) countries, with a particular interest on the diagnostic facilities in these countries.

    Authors: Nataša Toplak, Pavla Dolezalovà, Tamas Constantin, Anna Sedivà, Srdjan Pašić, Peter Čižnar, Beata Wolska-Kuśnierz, Miroslav Harjaček, Mariana Stefan, Nicolino Ruperto, Marco Gattorno and Tadej Avčin
    Citation: Pediatric Rheumatology 2010 8:29
  19. The antinuclear antibody test (ANA) is a much overused test in pediatrics. The ANA does have a role in serologic testing but it should be a very limited one. It is often ordered as a screening test for rheumat...

    Authors: Peter N Malleson, Murray J Mackinnon, Michaela Sailer-Hoeck and Charles H Spencer
    Citation: Pediatric Rheumatology 2010 8:27
  20. Juvenile idiopathic arthritis (JIA) is a heterogeneous condition and therapeutic strategies vary in different JIA types. The routinely accepted practice to start with Sulphasalazine (SS) as the first line trea...

    Authors: Valda Stanevicha, Jelena Eglite, Dace Zavadska, Arturs Sochnevs, Arina Lazareva, Dinara Guseinova, Ruta Shantere and Dace Gardovska
    Citation: Pediatric Rheumatology 2010 8:26
  21. We evaluated the effect of infliximab on markers of inflammation in patients with juvenile idiopathic arthritis (JIA).

    Authors: Sudha Visvanathan, Carrie Wagner, Joseph C Marini, Daniel J Lovell, Alberto Martini, Ross Petty, Ruben Cuttica, Patricia Woo, Graciela Espada, Marco Gattorno, Maria T Apaz, Eileen Baildam, Anders Fasth, Valeria Gerloni, Pekka Lahdenne, Pierre Quartier…
    Citation: Pediatric Rheumatology 2010 8:24
  22. More than 15 million people worldwide have rheumatic fever (RF) and rheumatic heart disease due to RF. Secondary prophylaxis is a critical cost-effective intervention for preventing morbidity and mortality rel...

    Authors: Christina F Pelajo, Jorge M Lopez-Benitez, Juliana M Torres and Sheila KF de Oliveira
    Citation: Pediatric Rheumatology 2010 8:22
  23. Takayasu arteritis is a large vessel systemic granulomatous vasculitis characterized by stenosis or obliteration of large and medium sized arteries. It commonly involves elastic arteries such as the aorta and ...

    Authors: Tahar Gargah, Mouna Ben Harrath, Haythem Bachrouche, Hatem Rajhi, Taeb Ben Abdallah and Mohamed R Lakhoua
    Citation: Pediatric Rheumatology 2010 8:21
  24. Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and ...

    Authors: Lakshmi N Moorthy, Margaret GE Peterson, Afton L Hassett and Thomas JA Lehman
    Citation: Pediatric Rheumatology 2010 8:20
  25. Rarely, systemic lupus erythematosus (SLE) presents with bullous lesions due to severe edema and hydropic degeneration of the basal layer, or as a subepidermal blistering disease. Here, we describe two Mexican...

    Authors: Marimar Sáez-de-Ocariz, Francisco Espinosa-Rosales, Eduardo López-Corella and Beatriz de León-Bojorge
    Citation: Pediatric Rheumatology 2010 8:19
  26. Concerns have been raised about a potential link between the use of TNF inhibitors and development of malignancy in the pediatric population. We examined the worldwide experience of etanercept use in pediatric...

    Authors: Peter McCroskery, Carol A Wallace, Daniel J Lovell, Scott Stryker, Nataliya Chernyukhin, Consuelo Blosch and Debra J Zack
    Citation: Pediatric Rheumatology 2010 8:18
  27. The original version of the Childhood Health Assessment Questionnaire (CHAQ30orig) suffers from a ceiling effect and hence has reduced clinical validity. The purpose of this study was to evaluate the effect of...

    Authors: W Groen, E Ünal, M Nørgaard, S Maillard, J Scott, K Berggren, E Sandstedt, M Stavrakidou and J van der Net
    Citation: Pediatric Rheumatology 2010 8:16
  28. Our earlier work in the ultrasonograpy of localized scleroderma (LS) suggests that altered levels of echogenicity and vascularity can be associated with disease activity. Utrasound is clinically benign and rea...

    Authors: Suzanne C Li, Melissa S Liebling, Faridali G Ramji, Sven Opitz, Arun Mohanta, Tatiana Kornyat, Shuzhen Zhang, Molly Dempsey-Robertson, Carsten Hamer, Stephanie Edgerton, Jose Jarrin, Mike Malone and Andrea S Doria
    Citation: Pediatric Rheumatology 2010 8:14
  29. To investigate the relationship between radiographic JIA disease course in the TMJs and mandibular growth rotation, compared with growth in healthy individuals.

    Authors: MG Fjeld, LZ Arvidsson, H-J Smith, B Flatø, B Øgaard and TA Larheim
    Citation: Pediatric Rheumatology 2010 8:13
  30. No consensus evidence-based guidelines for the routine laboratory monitoring of children with JIA receiving non-steroidal anti-inflammatory drugs (NSAIDs) exist. The purpose of this study is to evaluate the cl...

    Authors: Sheetal S Vora, Christine E Bengtson, Grant D Syverson and James J Nocton
    Citation: Pediatric Rheumatology 2010 8:11
  31. Sexually active adolescents, including young women with lupus, are at high risk for unplanned pregnancy. Unplanned pregnancy among teens with lupus is associated with an elevated risk of poor maternal and feta...

    Authors: Melissa S Tesher, Amy Whitaker, Melissa Gilliam, Linda Wagner-Weiner and Karen B Onel
    Citation: Pediatric Rheumatology 2010 8:10
  32. CINCA/NOMID is an autoinflammatory disorder characterized by the triad of neonatal onset of cutaneous symptoms, chronic meningitis, and recurrent fever and it presents with distinctive osteoarthropathy, synovi...

    Authors: Takako Miyamae, Yutaka Inaba, Gen Nishimura, Masako Kikuchi, Takayuki Kishi, Ryoki Hara, Utako Kaneko, Toshihiko Shinoki, Tomoyuki Imagawa and Shumpei Yokota
    Citation: Pediatric Rheumatology 2010 8:9
  33. We report on pediatric patient with clinical and laboratory evidence of pancreatitis at onset of atypical Kawasaki disease (KD). In KD pancreatic inflammation was described previously, but clinical pancreatiti...

    Authors: Dragan Prokic, Goran Ristic, Zoran Paunovic and Srdjan Pasic
    Citation: Pediatric Rheumatology 2010 8:8

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