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  1. Content type: Review

    Pediatric rheumatic diseases with predominant musculoskeletal involvement such as juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis(JDM) can cause considerable physical functional impairment and...

    Authors: Lakshmi Nandini Moorthy, Margaret GE Peterson, Melanie J Harrison, Karen B Onel and Thomas JA Lehman

    Citation: Pediatric Rheumatology 2008 6:9

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  2. Content type: Research

    Cytokines play important roles in mediating inflammation in autoimmunity. Several cytokines are elevated in serum and synovial fluid samples from children with Juvenile Idiopathic Arthritis (JIA). Soluble CD15...

    Authors: Sampath Prahalad, Thomas B Martins, Anne E Tebo, April Whiting, Bronte Clifford, Andrew S Zeft, Bernadette McNally, John F Bohnsack and Harry R Hill

    Citation: Pediatric Rheumatology 2008 6:8

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  3. Content type: Case Report

    The coexistence of systemic lupus erythematosus (SLE) in patients with congenital human immunodeficiency virus (HIV) infection is rare. This is a case report of a child diagnosed with SLE at nine years of age....

    Authors: Elizabeth C Chalom, Fariba Rezaee and Joel Mendelson

    Citation: Pediatric Rheumatology 2008 6:7

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  4. Content type: Research

    North American pediatric rheumatologists have created an investigator-initiated research network (the Childhood Arthritis and Rheumatology Research Alliance – CARRA) to facilitate multi-centre studies. One of ...

    Authors: Sylvia Ota, Randy Q Cron, Laura E Schanberg, Kathleen O'Neil, Elizabeth D Mellins, Robert C Fuhlbrigge and Brian M Feldman

    Citation: Pediatric Rheumatology 2008 6:5

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  5. Content type: Case Report

    Central nervous system involvement occurs in as many as twenty percent of Takayasu arteritis cases. When central nervous system disease is present, it typically manifests as cerebral ischemia or stroke. There ...

    Authors: Pamela F Weiss, Diana A Corao, Avrum N Pollock, Terri H Finkel and Sabrina E Smith

    Citation: Pediatric Rheumatology 2008 6:4

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  6. Content type: Case Report

    We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appea...

    Authors: Robert M Rennebohm, Martin Lubow, Jerome Rusin, Lisa Martin, Deborah M Grzybowski and John O Susac

    Citation: Pediatric Rheumatology 2008 6:3

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  7. Content type: Research

    Intra-articular corticosteroid injection in juvenile idiopathic arthritis (JIA) is often associated with anxiety and pain. Recent reports advocate the use of nitrous oxide (NO), a volatile gas with analgesic, ...

    Authors: Yosef Uziel, Gil Chapnick, Michal Rothschild, Tsivia Tauber, Joseph Press, Liora Harel and Philip J Hashkes

    Citation: Pediatric Rheumatology 2008 6:1

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  8. Content type: Research

    To investigate concordance between physicians and parents in rating the degree of functional ability of children with juvenile idiopathic arthritis (JIA).

    Authors: Elena Palmisani, Nicoletta Solari, Angela Pistorio, Nicolino Ruperto, Clara Malattia, Stefania Viola, Antonella Buoncompagni, Anna Loy, Alberto Martini and Angelo Ravelli

    Citation: Pediatric Rheumatology 2007 5:23

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  9. Content type: Research

    There are neither sensitive nor specific laboratory tests for measuring disease activity in localized scleroderma (LS). Monitoring is done almost exclusively by clinical assessment. Our aim was to determine wh...

    Authors: Yosef Uziel, Brian M Feldman, Bernice R Krafchik, Ronald M Laxer and Rae SM Yeung

    Citation: Pediatric Rheumatology 2007 5:22

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  10. Content type: Case Report

    Bullous systemic lupus erythematosus is a rare blistering condition with a distinctive combination of clinical, histological and immunopathologic features that together constitute a unique bullous disease phen...

    Authors: Sathish Kumar and Indira Agarwal

    Citation: Pediatric Rheumatology 2007 5:20

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  11. Content type: Letter to the Editor

    The increasing availability of the internet allows physicians to access actualized medical information quickly and easily, but it is not comparable with the possibility of working in a well known international...

    Authors: Pablo Garcia Munitis

    Citation: Pediatric Rheumatology 2007 5:18

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  12. Content type: Review

    Farber Disease is an autosomal-recessively inherited, lysosomal storage disorder caused by acid ceramidase deficiency and associated with distinct clinical phenotypes. Children with significant neurological in...

    Authors: Karoline Ehlert, Michael Frosch, Natalja Fehse, Axel Zander, Johannes Roth and Josef Vormoor

    Citation: Pediatric Rheumatology 2007 5:15

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  13. Content type: Review

    Juvenile idiopathic arthritis (JIA) has long been assumed to be an autoimmune disease, triggered by aberrant recognition of "self" antigens by T-cells. However, systems biology approaches to this family of dis...

    Authors: James N Jarvis, Kaiyu Jiang, Howard R Petty and Michael Centola

    Citation: Pediatric Rheumatology 2007 5:13

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  14. Content type: Case Report

    Cryopyrin-associated diseases may be characterized by rashes, fever, and sensorineural deafness, while celiac disease may present with symptoms of malabsorption and fatigue. Arthritis is seen in both condition...

    Authors: Marcus Shaker, Susan Edwards, Henry Chionuma, Eric Shamansky and Hal M Hoffman

    Citation: Pediatric Rheumatology 2007 5:12

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  15. Content type: Short Report

    Juvenile systemic sclerosis (JSS) is a multisystem connective tissue disease characterized by skin fibrosis and internal organ involvement. It has a low prevalence, even in a tertiary facility setting. The pur...

    Authors: Ricardo AG Russo and María M Katsicas

    Citation: Pediatric Rheumatology 2007 5:6

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  16. Content type: Review

    We review the clinical manifestations of "growing pains", the most common form of episodic childhood musculoskeletal pain. Physicians should be careful to adhere to clear clinical criteria as described in this...

    Authors: Yosef Uziel and Philip J Hashkes

    Citation: Pediatric Rheumatology 2007 5:5

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  17. Content type: Research

    Loss of joint cartilage is a feature of destructive disease in JIA. The cartilage of most joints can be visualized with ultrasonography (US). Our present study focuses on discriminant validity of US in childre...

    Authors: Anne Helene Spannow, Elisabeth Stenboeg, Mogens Pfeiffer-Jensen and Troels Herlin

    Citation: Pediatric Rheumatology 2007 5:3

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  18. Content type: Research

    An increased concentration of plasma homocysteine (Hcy) has toxic effects on vascular endothelium. This seems to be a risk factor of cardiovascular disease, premature stroke and venous thrombosis. The risk is ...

    Authors: Marcela Gonçalves, Vânia D'Almeida, Elvira M Guerra-Shinohara, Luciano C Galdieri, Claudio A Len and Maria Odete E Hilário

    Citation: Pediatric Rheumatology 2007 5:2

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