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Table 2 Laboratory and echocardiographic findings among the studied patients and subgroups

From: Aquaporin-4 IgG antibodies: predictors of positivity and their relationship with neuropsychiatric disorders and white matter lesions in Juvenile systemic lupus erythematosus

 

All patients

(n = 90)

Anti-AQP4 Ab negative subgroup

(n = 34)

Anti-AQP4 Ab positive subgroup

(n = 56)

Test of significance

WBC count

6.85 (4.93–9.33)

6.75(2.4–24)

7.0(3.0-26.8)

p = 0.677

Neutrophil number

4.2 (2.8-5)

4.1(1-15.5)

4.2(1.6–18)

p = 0.680

Lymphocyte number

2.0 (1.2–3.5)

1.85(0.4–10)

2.1(0.48–6.3)

p = 0.848

HB level

9.29 ± 1.76

9.52 ± 1.63

9.16 ± 1.84

p = 0.347

Platelet count

190 (117.5-280.25)

189(10–540)

190(63–701)

p = 0.479

MPV

8.7 (7.15–10.83)

8.45(5.4–14.5)

8.75(5-12.6)

p = 0.878

Proteinuria %

73.3

55.9

83.9

p = 0.004*

ESR first hour

104.5 (86-125.25)

65(20–120)

75(35–145)

p = 0.142

CRP

6 (3-18.25)

5.5(1–56)

7.5(1–96)

p = 0.184

C3

53(40.75-63)

60(37.0-137)

48.5(22–108)

p = 0.006*

C4

12.5 (8–17)

12.5(1.0–52.0)

12.5(1.0–45.0)

p = 0.275

ANA %

90 (100%)

34(100)

56(100)

P = 1.0

Anti dsDNA%

70 (77.8%)

27(79.4)

43(76.8)

p = 0.771

LA %

26 (28.9%)

6(17.6)

20(35.7)

p = 0.067

ACL %

63 (70%)

20(58.8)

43(76.8)

p = 0.07

Patients who underwent echocardiography examination %

57.8

41.2

67.9

p = 0.013*

Pericarditis %

42.2

26.5

251.8

p = 0.018*

Valvular %

22.2

17.6

25

p = 0.416

Endocarditis %

11.1

5.9

14.3

p = 0.219

Myocarditis %

8.9

5.9

10.7

p = 0.435

  1. WBC: white blood cell, HB: haemoglobin, MPV: mean platelet volume, ESR: erythrocyte sedimentation rate, CRP: c-reactive protein. C3: complement 3, C4: complement 4, ANA: antinuclear antibody, Anti dsDNA: anti double-stranded antibodies, LA: lupus anticoagulant, ACL: anticardiolipin. p < 0.05 was considered statistically significant