Table 1 Comparison of demographic, clinical characteristics, and laboratory findings between CAL group and non-CAL group
|  | Total N = 66 | CAL group N = 26 | non-CAL group N = 40 | P values |
|---|---|---|---|---|
Age of onset, months | 85.2 (12.0-133.8) | 12.0 [3.1–48.7] | 115.6[82.1–146.0] | < 0.001 |
Gender | Â | Â | Â | Â |
female, n (%) | 43 (65.2) | 18 (61.2) | 25 (62.5) | 0.77 |
Symptom onset to diagnosis, day | 20.0 (8.0-31.5) | 11.5 [7.0–20.0] | 28.0 [14.8–60.0] | 0.01 |
Clinical manifestation, n (%) | Â | Â | Â | Â |
 Fever | 38 (57.6) | 18 (69.2) | 20 (50.0) | 0.20 |
 No pulse/weak pulse | 18 (27.3) | 7 (26.9) | 11 (27.5) | 1.00 |
 Hypertension | 30 (45.5) | 8 (30.8) | 22 (55.0) | 0.09 |
 Malaise | 10 (15.2) | 2 (7.7) | 8 (20.0) | 0.31 |
 vascular murmur | 14 (21.2) | 4 (15.4) | 10 (25.0) | 0.53 |
Laboratory findings | Â | Â | Â | Â |
 CRP, mg/L | 41.5 [3.8-105.3] | 64.5 [22.2-139.8] | 25.0 [3.2–82.5] | 0.04 |
 AESR, mm/h | 46.0 [12.5–89.5] | 47.5 [18.2–86.0] | 41.5 [11.8–95.0] | 0.78 |
 WBC, 10^9/L | 10.3 [7.8–16.5] | 13.9 [9.9–18.8] | 8.7 [7.3–12.1] | 0.002 |
 HGB, g/L | 106.7 ± 21.3 | 99.4 ± 19.8 | 111.4 ± 21.1 | 0.02 |
 PLT, 10^9/L | 401.0 [278.3-512.8] | 481.5 [310.8-596.5] | 346.5 [253.2-428.8] | 0.01 |
 FIB, g/L(2–4) | 11.0 [9.0-17.7] | 3.5[3.0-4.7] | 4.9[2.9–4.6] | 0.95 |
 Na, mmol/L(135–145) | 8.5 [4.7–20.0] | 139.0[136.0-140.8] | 139.9[136.0-141.0] | 0.95 |
 Albumin, g/l(35–55) | 408.5 [341.5–659.0] | 37.1[32.5–41.1] | 39.5[36.0-43.1] | 0.11 |
 TNF-a, pg/mL | 27.0 [15.0–37.0] | 14.4 [10.6–18.6] | 10.0 [7.9–16.0] | 0.01 |
 IL-6, pg/mL | 157.0 [89.0-292.3] | 12.1 [6.1–26.0] | 7.7 [4.4–15.8] | 0.06 |
 IL-2R, pg/mL | 3.0 [3.0–3.0] | 527.0 [365.5-1547.2] | 380.0 [292.2-566.5] | 0.03 |
 IL-8, pg/mL | 27.0 [15.0–37.0] | 26.0 [15.0–37.0] | 27.5 [15.8–40.5] | 0.71 |
 FS, ng/mL | 157.0 [89.0-292.3] | 195.5 [94.0-385.5] | 123.0 [87.2-238.2] | 0.16 |
NIH score,(mean ± SD) | 3.0 [3.0–3.0] | 3.0 [2.0–3.0] | 3.0 [3.0–3.0] | 0.29 |
 Numano classification, n (%) |  |  |  | 0.60 |
  1 | 24(36.4) | 11 (42.3) | 13 (32.5) |  |
  2 | 9(13.6) | 4 (15.4) | 5 (12.5) |  |
  3 | 33(50.0) | 11 (42.3) | 22 (55.0) |  |
  4 | 0 | 0 | 0 |  |
Carotid artery stenosis(CAS), n (%) | 8 (12.1) | 3 (11.5) | 5 (12.5) | 1.00 |
Aorticinsufficiency, n (%) | 1(1.5) | 0 (0.0) | 1 (2.5) | 1.00 |
Aortectasia, n (%) | 1(1.5) | 0 (0.0) | 1 (2.5) | 1.00 |
Thoracic aortic stenosis (TAS), n (%) | 9 (13.6) | 3 (11.5) | 6 (15.0) | 0.97 |
Abdominal aortic stenosis (AAS), n (%) | 9 (13.6) | 2 (7.7) | 7 (17.5) | 0.44 |
Renal artery stenosis (RAS), n (%) | 24 (36.4) | 4 (15.4) | 20 (50.0) | 0.009 |
Renal hypoperfusion, n (%) | 6 (9.1) | 1 (3.8) | 5 (12.5) | 0.45 |