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Table 1 Laboratory test results over time

From: Why so low? An unusual case of myositis in a child

Laboratory Test (normal range)

Visit 1

Visit 2

Visit 3

Visit 4

Visit 5

Age 6

Age 12

Age 15

Age 15

(2 months after starting glucocorticoids; methotrexate prescribed at visit)

Age 16

(1 month after stopping medications)

Erythrocyte Sedimentation Rate (0–29 mm/hr)

120 (H)

112 (H)

107 (H)

28 (H)

84 (H)

C-Reactive Protein (0-0.9 mg/dL)

7.2 (H)

7.0 (H)

7.5 (H)

1.6 (H)

14.6 (H)

IgG (700–1600 mg/dL)

-

4040 (H)

3240 (H)

2597 (H)

2540 (H)

White Blood Cell Count (5-103/mcL)

7.7

9.28 (H)

11 (H)

10.9 (H)

10.46 (H)

Hemoglobin (12.1–15.1 g/dL)

10.1 (L)

9.1 (L)

9.1 (L)

10.6 (L)

9.4 (L)

Platelets (150–400 × 109/L)

504 (H)

603 (H)

664 (H)

527 (H)

617 (H)

Mean Corpuscular Volume (81–88 fL)

67.8 (L)

65.6 (L)

64.9 (L)

68.8 (L)

64.9 (L)

Creatine Kinase (22–198 U/L)

26

26

30

278 (H)

38

Lactate Dehydrogenase (varies, U/L)

378 (L)

350 (L)

276 (L)

319 (L)

-

Aspartate Aminotransferase (5–30 U/L)

-

39

49 (H)

23

21

Alanine Aminotransferase (10–35 U/L)

-

15

19

14

9 (L)

Complement C3 (80–160 mg/dL)

-

191 (H)

181 (H)

-

-

Complement C4 (12–42 mg/dL)

 

61.9 (H)

68.4 (H)

  

Lupus Anti-Coagulant (≤1.21 ratio)

-

(Negative in 2018)

1.28 (H)

-

-

d-Dimer (< 0.5 µg/mL)

-

-

0.92 (H)

< 0.27 (H)

0.82 (H)

Partial Thromboplastin Time (25–35 s)

34

-

35.5 (H)

35.5 (H)

43.9 (H)

Prothrombin Time (11-13.5 s)

15.8 (H)

-

15.1 (H)

-

15.1 (H)

International Normalized Ratio (< 1.1)

1.21

-

1.2

-

1.21

Additional labs checked during her course

Negative: antinuclear antibody profile, anti-β-2 glycoprotein-1 immunoglobulin G, anti-β-2 glycoprotein-1 immunoglobulin M, anti-cardiolipin immunoglobulin G, anti-cardiolipin immunoglobulin M, anti-myeloperoxidase antibody, anti-serine protease 3 antibody, myositis antibody panel, tissue transglutaminase immunoglobulin A

Normal: aldolase, angiotensin converting enzyme, eosinophil counts, lysozyme, serum calcium, uric acid, urinalysis with microscopy, urine protein to creatinine ratio, von Willebrand factor antigen