Laboratory Test (normal range) | Visit 1 | Visit 2 | Visit 3 | Visit 4 | Visit 5 |
---|---|---|---|---|---|
Age 6 | Age 12 | Age 15 | Age 15 (2 months after starting glucocorticoids; methotrexate prescribed at visit) | Age 16 (1 month after stopping medications) | |
Erythrocyte Sedimentation Rate (0–29 mm/hr) | 120 (H) | 112 (H) | 107 (H) | 28 (H) | 84 (H) |
C-Reactive Protein (0-0.9Â mg/dL) | 7.2 (H) | 7.0 (H) | 7.5 (H) | 1.6 (H) | 14.6 (H) |
IgG (700–1600 mg/dL) | - | 4040 (H) | 3240 (H) | 2597 (H) | 2540 (H) |
White Blood Cell Count (5-103/mcL) | 7.7 | 9.28 (H) | 11 (H) | 10.9 (H) | 10.46 (H) |
Hemoglobin (12.1–15.1 g/dL) | 10.1 (L) | 9.1 (L) | 9.1 (L) | 10.6 (L) | 9.4 (L) |
Platelets (150–400 × 109/L) | 504 (H) | 603 (H) | 664 (H) | 527 (H) | 617 (H) |
Mean Corpuscular Volume (81–88 fL) | 67.8 (L) | 65.6 (L) | 64.9 (L) | 68.8 (L) | 64.9 (L) |
Creatine Kinase (22–198 U/L) | 26 | 26 | 30 | 278 (H) | 38 |
Lactate Dehydrogenase (varies, U/L) | 378 (L) | 350 (L) | 276 (L) | 319 (L) | - |
Aspartate Aminotransferase (5–30 U/L) | - | 39 | 49 (H) | 23 | 21 |
Alanine Aminotransferase (10–35 U/L) | - | 15 | 19 | 14 | 9 (L) |
Complement C3 (80–160 mg/dL) | - | 191 (H) | 181 (H) | - | - |
Complement C4 (12–42 mg/dL) |  | 61.9 (H) | 68.4 (H) |  |  |
Lupus Anti-Coagulant (≤1.21 ratio) | - | (Negative in 2018) | 1.28 (H) | - | - |
d-Dimer (< 0.5 µg/mL) | - | - | 0.92 (H) | < 0.27 (H) | 0.82 (H) |
Partial Thromboplastin Time (25–35 s) | 34 | - | 35.5 (H) | 35.5 (H) | 43.9 (H) |
Prothrombin Time (11-13.5Â s) | 15.8 (H) | - | 15.1 (H) | - | 15.1 (H) |
International Normalized Ratio (< 1.1) | 1.21 | - | 1.2 | - | 1.21 |
Additional labs checked during her course | Negative: antinuclear antibody profile, anti-β-2 glycoprotein-1 immunoglobulin G, anti-β-2 glycoprotein-1 immunoglobulin M, anti-cardiolipin immunoglobulin G, anti-cardiolipin immunoglobulin M, anti-myeloperoxidase antibody, anti-serine protease 3 antibody, myositis antibody panel, tissue transglutaminase immunoglobulin A Normal: aldolase, angiotensin converting enzyme, eosinophil counts, lysozyme, serum calcium, uric acid, urinalysis with microscopy, urine protein to creatinine ratio, von Willebrand factor antigen |