Impaired cardiorespiratory and neuromuscular fitness in children and adolescents with juvenile idiopathic arthritis: a cross-sectional case–control study in the era of biologic drug therapies

Table 3 Physical fitness in JIA in relation to disease activity^a (mean ± SD) and healthy controls

	Inactive disease^a		Active disease^a		Controls
	n = 39 (53%)		n = 34 (47%)		n = 73
Participant characteristics
Age, years	11.9 ± 3.18		11.6 ± 2.84		11.7 ± 3.15
Gender
Male	13 (33%)		12 (35%)		25 (34%)
Female	26 (67%)		22 (65%)		48 (66%)
Ergospirometry		n		n		n
W_max,, Watts	124 ± 36.6	37	115 ± 43.4*	32	139 ± 50.9	72
W_max/kg, Watts/kg	2.87 ± 0.56*	37	2.72 ± 0.51*	32	3.14 ± 0.50	72
VO2_peak, l/min	1.70 ± 0.53*	34	1.61 ± 0.61*	32	2.18 ± 0.56	52
VO2_peak/kg, ml/min/kg	39.3 ± 7.56*	34	38.0 ± 7.56*	32	45.8 ± 6.59	52
Neuromuscular tests
Shuttle run, s	23.9 ± 2.73*	39	25.1 ± 4.34*	33	21.6 ± 1.93	67
Sit-ups, number/30 s	15.1 ± 5.68*	39	14.0 ± 5.42*	33	18.1 ± 5.61	70
Handgrip strength, kPa
Right	66.1 ± 13.4	39	64.4 ± 9.78	32	75.3 ± 28.0	73
Left,	63.7 ± 12.5*	39	63.8 ± 9.71*	32	74.1 ± 28.6	73
Standing long jump, m	1.41 ± 0.28*	39	1.43 ± 0.32*	32	1.60 ± 0.34	68
Box and block, number/min
Right	67.0 ± 27.0	39	65.5 ± 22.4	34	75.3 ± 28.0	73
Left,	64.4 ± 27.3*	39	64.2 ± 21.8*	34	74.1 ± 28.6	73
Balance test support/30 s	2.08 ± 1.99	39	1.93 ± 1.98	30	1.85 ± 1.73	52
Physical activity min/day
Active time	89.2 ± 48.9	32	88.8 ± 40.5	30	112 ± 62.6	71
Sedentary time	423 ± 198	34	431 ± 231	31	343 ± 211	70

W_max Maximal workload, VO2_peak Peak oxygen uptake
^a JADAS-10 (Juvenile idiopathic arthritis Disease Activity Score cut off- values): -inactive disease JADAS-10 < 0.6 in oligoarthritis and JADAS-10 < 0.8 in polyarthritis; -active disease JADAS-10 ≥ 0.6 in oligoarthritis and JADAS-10 ≥ 0.8 in polyarthritis
^*p < 0.05 vs. controls

ISSN: 1546-0096