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Table 1 Demographics and clinical characteristics of pSLE patients (N = 146)

From: Clinical phenotypes and prognosis of cytomegalovirus infection in the pediatric systemic lupus erythematosus: a longitudinal analysis

Features

CMV positive group

(N = 109)

CMV negative group

(N = 37)

OR (95%CI)

P value

Demographic Data

 Age of diagnosis (mean±SD)

11.81±2.07

12.33±1.91

-0.52a (-1.29;0.24)

0.18

 Female (%)

87(79.8)

28(75.7)

1.27 (0.53;3.08)

0.595

 New-onset (%)

46(42.2)

9(24.3)

2.27 (0.98;5.27)

0.052

Clinical manifestations

 Fever (%)

47(43.1)

7(18.9)

3.25 (1.31;8.04)

0.008

 Mucocutaneous (%)

71(65.1)

20(54.1)

1.59 (0.75;3.39)

0.229

 Musculoskeletal (%)

47(43.1)

7(18.9)

3.25 (1.31;8.04)

0.008

 Renal (%)

69(63.3)

21(56.8)

1.31 (0.62;2.81)

0.479

 Pleuropulmonary (%)

58(53.2)

16(43.2)

1.49 (0.7;3.16)

0.295

 Gastrointestinal (%)

13(11.9)

1(2.7)

4.88 (0.62;38.62)

0.118

 Neuropsychiatric (%)

33(30.3)

14(37.8)

0.71 (0.33;1.56)

0.395

 Cardiovascular (%)

42(38.5)

8(21.6)

2.27 (0.95;5.44)

0.061

 Hematological (%)

87(79.8)

24(64.9)

2.14 (0.94;4.87)

0.066

 Endocrine (%)

30(27.5)

11(29.7)

0.9 (0.4;2.04)

0.796

  1. Data are presented as mean ± standard deviation or count (percentage)
  2. CI Confidence interval, CMV Cytomegalovirus, OR Odds ratio, SLEDAI-2K Systemic Lupus Erythematosus Disease Activity Index 2000
  3. aMedian difference