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Table 1 Demographic and clinical characteristics of patients with SLE at the time of diagnosis

From: Risk factors for subsequent lupus nephritis in patients with juvenile-onset systemic lupus erythematosus: a retrospective cohort study

 

Total (N = 48)

Group 1 (N = 20)

Group 2 (N = 28)

p-value

Female gender, n (%)

42 (87.5)

18 (90.0)

24 (85.7)

1

Age at SLE diagnosis (years), mean (SD)

13.16 (2.4)

13.08 (2.1)

13.21(2.6)

0.855

Duration of follow-up (years), mean (SD)

5.32 (2.7)

4.63 (2.8)

5.82 (2.7)

0.140

Time to LN, median (range)

 

4.28 (0.8–12.1)

NA

 

Age at LN diagnosis (years)

 

17.85 (11.9–26.8)

NA

 

Clinical manifestations (at SLE diagnosis), n (%)

 Malar rash

 

12 (60.0)

15 (53.6)

0.771

 Discoid rash

 

1 (5.0)

9 (32.1)

0.031

 Photosensitivity

 

5 (25.0)

6 (21.4)

1

 Oral ulcers

 

8 (40.0)

8 (28.6)

0.537

 Arthritis

 

14 (70.0)

16 (57.1)

0.546

 Serositis

 

4 (20.0)

3 (10.7)

0.429

 Seizure/ psychosis

 

1 (5.0)

2 (7.1)

1

 Hematologic

 

14 (70.0)

22 (78.6)

0.520

 Immunologic

 

20 (100)

26 (92.9)

0.503

 Antinuclear antibody

 

20 (100)

27 (96.4)

1

 Hepatitis

 

3 (15.0)

5 (17.9)

1

Hemogram (at SLE diagnosis), n (%)

 Leukopeniaa

 

3 (21.4)

9 (33.3)

0.494

 Lymphopeniab

 

9 (64.3)

14 (51.9)

0.520

 Thrombocytopeniac

 

3 (20)

5 (18.5)

1

  1. Mean and SD (standard deviation) are presented for quantitative and ordinal data
  2. aLeukopenia was defined as white blood cell count < 4000/ µL
  3. bLymphopenia was defined as absolute lymphocyte count < 1500/ µL
  4. cThrombocytopenia was defined as platelet count < 100,000/ µL