Table 3 Associated factors and independent predictors for AITD on univariable and multivariable analysis

Family history of AITD

7.43

4.56 – 11.74^c

Female sex

2.36

1.42 – 4.19^c

ANA positive

1.77

1.16 – 2.71^c

Age at JIA onset in years

1.10

1.05 – 1.15^c

Observation period in years^a

1.02

0.98 – 1.07

 European

1.00

Reference

 Sub-Saharan African

–

–

 Hispanic

0.32

0.02 – 1.44

 Indian

0.55

0.03 – 2.48

 Middle Eastern

1.22

0.30 – 3.30

 Multiethnic

0.72

0.04 – 3.29

 North African

1.04

0.17 – 3.32

 Southeast Asian

–

–

 Other

1.68

0.09 – 7.80

Family history of autoimmune disease

2.59

1.71 – 3.93^c

 Oligoarthritis

1.00

Reference

 Enthesitis-related arthritis

0.87

0.37 – 1.80

 Polyarthritis (RF-)

1.34

0.81 – 2.21

 Polyarthritis (RF+)

2.62

1.17 – 5.31^c

 Psoriatic arthritis

2.14

0.80 – 4.81

 Systemic arthritis

0.22

0.03 – 0.71^c

 Undifferentiated arthritis

1.53

0.68 – 3.09

Active joint count at diagnosis^b

0.99

0.82 – 1.07

RF positive

2.49

1.15 – 4.73^c

HLA-B27 positive

0.71

0.31 – 1.43

 NSAIDs

0.87

0.54 – 1.49

 Intraarticular corticosteroids

1.01

0.68 – 1.52

 Systemic corticosteroids

0.71

0.46 – 1.09

 cs-DMARDs

0.96

0.55 – 1.81

 Methotrexate

0.83

0.51 – 1.43

 b-DMARDs

1.24

0.80 – 1.95

 Anti-TNF

1.49

0.98 – 2.32